Porpus: Ein kurzer, alltagstauglicher und valider Lebensqualitätsfragebogen zur Erfassung prostataspezifischer Symptome

Introduction: In German-speaking countries only one validated questionnaire asking for prostate-specific quality of life existed until summer 2009 (PSM; but since then the German version of EORTC QLQ-PR25 was available). After a translation of the English version of PORPUS into German we wanted to show psychometric properties of the translated questionnaire. Materials and Methods: Sensitivity to change and validity were proven with data from the San-BKK- (general population, one questioning), the CHEDY- (men with erectile dysfunction, one questioning) and the ProCaSP-study (men with localized prostate cancer [PCa]), initial questioning and 4 follow-up surveys within 2 years). Each study focused on quality of life as a primary endpoint. Quality of life was measured with multiple questionnaires, e. g. EORTC QLQC30, EQ-5D, and PORPUS-P. Results: Data were derived from 988 men of the general population (mean age 56 years), 87 PCa-patients with radiotherapy (67 years), 274 PCa-patients with radical prostate ectomy (63 years), and 48 men with erectile dysfunction (58 years). Different quality of life-scales correlated with each other and proved convergence validity (PORPUS-P vs. EORTC QLQ-C30 global health, EQ-5D VAS and EQ-5D index value; range r_s = 0.518-0.630; each p < 0.001). Furthermore, PORPUS-P differed between age groups, health status, and social subgroups. The distribution of answers in the general population indicated sensitivity to change as well as the changes of answering patterns and changes of PORPUS-P in men with PCa (follow up for 2 years). Approximately 3.5 minutes are needed to complete PORPUS (10 items). Conclusion: PORPUS is another valid German questionnaire to evaluate prostate-specific quality of life. The advantage of PORPUS is its briefness, which allows a good acceptance and fits in busy clinical routines.