Physical and FEM Simulation of Microprobe Insertion into Rat Brain

A. E. Olamat; N. Nkemasong; B. M. Pohl; U. G. Hofmann

Physical and FEM Simulation of Microprobe Insertion into Rat Brain

A. E. Olamat, N. Nkemasong, B. M. Pohl, U. G. Hofmann

Institut für Signalverarbeitung

Abstract

In order to investigate theimplantation of microprobes into brain tissue, wedeveloped a finite-element and a physical modelto replace real biological tissue for mechanicaltesting. Penetrating forces of a tungsten indenterinto a layered structure was investigated withdifferent indentation speeds. Numerical andphysical model are in good correspondence toeach other and reproduce measured brainelasticity (15kPa) and dimpling effects followedby rupturing of the top layer well. We suggestfor future mechanical evaluation of brain probesto first utilize model structures before sacrificinganimals.

Originalsprache	Englisch
Seitenumfang	5
Publikationsstatus	Veröffentlicht - 01.11.2010
Veranstaltung	European COMSOL Conference 2010 - the Palais des congrès de Versailles, Paris, Frankreich Dauer: 17.11.2010 → 19.11.2010

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Tagung, Konferenz, Kongress	European COMSOL Conference 2010
Land/Gebiet	Frankreich
Ort	Paris
Zeitraum	17.11.10 → 19.11.10

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Olamat, A. E., Nkemasong, N., Pohl, B. M., & Hofmann, U. G. (2010). Physical and FEM Simulation of Microprobe Insertion into Rat Brain. Beitrag in European COMSOL Conference 2010, Paris, Frankreich. https://www.researchgate.net/profile/Ulrich_Hofmann3/publication/230603382_Physical_and_FEM_simulation_of_microprobe_insertion_into_rat_brain/links/0fcfd50cb765926a42000000/Physical-and-FEM-simulation-of-microprobe-insertion-into-rat-brain.pdf

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title = "Physical and FEM Simulation of Microprobe Insertion into Rat Brain",

abstract = "In order to investigate theimplantation of microprobes into brain tissue, wedeveloped a finite-element and a physical modelto replace real biological tissue for mechanicaltesting. Penetrating forces of a tungsten indenterinto a layered structure was investigated withdifferent indentation speeds. Numerical andphysical model are in good correspondence toeach other and reproduce measured brainelasticity (15kPa) and dimpling effects followedby rupturing of the top layer well. We suggestfor future mechanical evaluation of brain probesto first utilize model structures before sacrificinganimals. ",

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Olamat, AE, Nkemasong, N, Pohl, BM & Hofmann, UG 2010, 'Physical and FEM Simulation of Microprobe Insertion into Rat Brain', Beitrag in European COMSOL Conference 2010, Paris, Frankreich, 17.11.10 - 19.11.10. <https://www.researchgate.net/profile/Ulrich_Hofmann3/publication/230603382_Physical_and_FEM_simulation_of_microprobe_insertion_into_rat_brain/links/0fcfd50cb765926a42000000/Physical-and-FEM-simulation-of-microprobe-insertion-into-rat-brain.pdf>

TY - CONF

T1 - Physical and FEM Simulation of Microprobe Insertion into Rat Brain

AU - Olamat, A. E.

AU - Nkemasong, N.

AU - Pohl, B. M.

AU - Hofmann, U. G.

PY - 2010/11/1

Y1 - 2010/11/1

N2 - In order to investigate theimplantation of microprobes into brain tissue, wedeveloped a finite-element and a physical modelto replace real biological tissue for mechanicaltesting. Penetrating forces of a tungsten indenterinto a layered structure was investigated withdifferent indentation speeds. Numerical andphysical model are in good correspondence toeach other and reproduce measured brainelasticity (15kPa) and dimpling effects followedby rupturing of the top layer well. We suggestfor future mechanical evaluation of brain probesto first utilize model structures before sacrificinganimals.

AB - In order to investigate theimplantation of microprobes into brain tissue, wedeveloped a finite-element and a physical modelto replace real biological tissue for mechanicaltesting. Penetrating forces of a tungsten indenterinto a layered structure was investigated withdifferent indentation speeds. Numerical andphysical model are in good correspondence toeach other and reproduce measured brainelasticity (15kPa) and dimpling effects followedby rupturing of the top layer well. We suggestfor future mechanical evaluation of brain probesto first utilize model structures before sacrificinganimals.

UR - https://www.researchgate.net/publication/230603382_Physical_and_FEM_simulation_of_microprobe_insertion_into_rat_brain

M3 - Conference Papers

T2 - European COMSOL Conference 2010

Y2 - 17 November 2010 through 19 November 2010

ER -

Physical and FEM Simulation of Microprobe Insertion into Rat Brain

Abstract

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