TY - JOUR
T1 - Pemphigus herpetiformis
T2 - From first description until now
AU - Kasperkiewicz, Michael
AU - Kowalewski, Cezary
AU - Jabłońska, Stefania
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Pemphigus herpetiformis is one of the less common forms of pemphigus, first introduced by Jabłońska and colleagues in 1975. This autoimmune bullous disease combines the clinical features of dermatitis herpetiformis and the immunologic characteristics of pemphigus. The target autoantigen is usually desmoglein 1 (or less frequently desmoglein 3), although recently it has become increasingly obvious that patients with pemphigus herpetiformis also demonstrate autoantibodies against desmocollin. Here, we summarize reported cases of pemphigus herpetiformis and describe current knowledge considering epidemiology, clinical manifestations, histologic findings, immunopathology, pathophysiologic concepts, associated diseases, and treatment of this rare disorder.
AB - Pemphigus herpetiformis is one of the less common forms of pemphigus, first introduced by Jabłońska and colleagues in 1975. This autoimmune bullous disease combines the clinical features of dermatitis herpetiformis and the immunologic characteristics of pemphigus. The target autoantigen is usually desmoglein 1 (or less frequently desmoglein 3), although recently it has become increasingly obvious that patients with pemphigus herpetiformis also demonstrate autoantibodies against desmocollin. Here, we summarize reported cases of pemphigus herpetiformis and describe current knowledge considering epidemiology, clinical manifestations, histologic findings, immunopathology, pathophysiologic concepts, associated diseases, and treatment of this rare disorder.
UR - http://www.scopus.com/inward/record.url?scp=84896076403&partnerID=8YFLogxK
U2 - 10.1016/j.jaad.2013.11.043
DO - 10.1016/j.jaad.2013.11.043
M3 - Journal articles
C2 - 24472428
AN - SCOPUS:84896076403
SN - 0190-9622
VL - 70
SP - 780
EP - 787
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 4
ER -