TY - JOUR
T1 - Oral toxicity management in head and neck cancer patients treated with chemotherapy and radiation
T2 - Xerostomia and trismus (Part 2). Literature review and consensus statement
AU - Buglione, Michela
AU - Cavagnini, Roberta
AU - Di Rosario, Federico
AU - Maddalo, Marta
AU - Vassalli, Lucia
AU - Grisanti, Salvatore
AU - Salgarello, Stefano
AU - Orlandi, Ester
AU - Bossi, Paolo
AU - Majorana, Alessandra
AU - Gastaldi, Giorgio
AU - Berruti, Alfredo
AU - Trippa, Fabio
AU - Nicolai, Pietro
AU - Barasch, Andrei
AU - Russi, Elvio G.
AU - Raber-Durlacher, Judith
AU - Murphy, Barbara
AU - Magrini, Stefano M.
PY - 2016/6/1
Y1 - 2016/6/1
N2 - Radiotherapy alone or in combination with chemotherapy and/or surgery is a well-known radical treatment for head and neck cancer patients. Nevertheless acute side effects (such as moist desquamation, skin erythema, loss of taste, mucositis etc.) and in particular late toxicities (osteoradionecrosis, xerostomia, trismus, radiation caries etc.) are often debilitating and underestimated.A multidisciplinary group of head and neck cancer specialists from Italy met in Milan with the aim of reaching a consensus on a clinical definition and management of these toxicities.The Delphi Appropriateness method was used for this consensus and external experts evaluated the conclusions. The paper contains 20 clusters of statements about the clinical definition and management of stomatological issues that reached consensus, and offers a review of the literature about these topics.The review was split into two parts: the first part dealt with dental pathologies and osteo-radionecrosis (10 clusters of statements), whereas this second part deals with trismus and xerostomia (10 clusters of statements).
AB - Radiotherapy alone or in combination with chemotherapy and/or surgery is a well-known radical treatment for head and neck cancer patients. Nevertheless acute side effects (such as moist desquamation, skin erythema, loss of taste, mucositis etc.) and in particular late toxicities (osteoradionecrosis, xerostomia, trismus, radiation caries etc.) are often debilitating and underestimated.A multidisciplinary group of head and neck cancer specialists from Italy met in Milan with the aim of reaching a consensus on a clinical definition and management of these toxicities.The Delphi Appropriateness method was used for this consensus and external experts evaluated the conclusions. The paper contains 20 clusters of statements about the clinical definition and management of stomatological issues that reached consensus, and offers a review of the literature about these topics.The review was split into two parts: the first part dealt with dental pathologies and osteo-radionecrosis (10 clusters of statements), whereas this second part deals with trismus and xerostomia (10 clusters of statements).
UR - http://www.scopus.com/inward/record.url?scp=84962544063&partnerID=8YFLogxK
U2 - 10.1016/j.critrevonc.2016.03.012
DO - 10.1016/j.critrevonc.2016.03.012
M3 - Scientific review articles
C2 - 27061883
AN - SCOPUS:84962544063
SN - 1040-8428
VL - 102
SP - 47
EP - 54
JO - Critical Reviews in Oncology/Hematology
JF - Critical Reviews in Oncology/Hematology
ER -