Obese patients with NASH have increased hepatic expression of SARS-CoV-2 critical entry points

Marcos F. Fondevila; Maria Mercado-Gómez; Amaia Rodríguez; Maria J. Gonzalez-Rellan; Paula Iruzubieta; Víctor Valentí; Javier Escalada; Markus Schwaninger; Vincent Prevot; Carlos Dieguez; Javier Crespo; Gema Frühbeck; Maria L. Martinez-Chantar; Ruben Nogueiras

doi:10.1016/j.jhep.2020.09.027

Obese patients with NASH have increased hepatic expression of SARS-CoV-2 critical entry points

Marcos F. Fondevila, Maria Mercado-Gómez, Amaia Rodríguez, Maria J. Gonzalez-Rellan, Paula Iruzubieta, Víctor Valentí, Javier Escalada, Markus Schwaninger, Vincent Prevot, Carlos Dieguez, Javier Crespo, Gema Frühbeck, Maria L. Martinez-Chantar^*, Ruben Nogueiras

^*Korrespondierende/r Autor/-in für diese Arbeit

Institut für Experimentelle und Klinische Pharmakologie und Toxikologie

56 Zitate (Scopus)

Originalsprache	Englisch
Zeitschrift	Journal of Hepatology
Jahrgang	74
Ausgabenummer	2
Seiten (von - bis)	469-471
Seitenumfang	3
ISSN	0168-8278
DOIs	https://doi.org/10.1016/j.jhep.2020.09.027
Publikationsstatus	Veröffentlicht - 02.2021

Fördermittel

This work has been supported by grants from FEDER/Ministerio de Ciencia, Innovaci?n y Universidades-Agencia Estatal de Investigaci?n (CD: BFU2017-87721; RN: RTI2018-099413-B-I00; MLMC: SAF2017-87301-R; Xunta de Galicia (RN: 2015-CP080 and 2016-PG057) and ED431G 2019/02, Fundaci?n BBVA (RN and MLM), Fundaci?n Atresmedia (RN), and European Foundation for the Study of Diabetes (RN). FIS: PI18/0130. Immunomediatd Nonalcoholic SteaTohepatItis; prevalence and CharacTerization. INSTInCT study (PI: Javier Crespo). Intensificaci?n IDIVAL I-1 (Javier Crespo). The research leading to these results has also received funding from the European Community's H2020 Framework Programme under the following grant: ERC Synergy Grant-2019-WATCH- 810331 to MS, VP and RN. CIBERobn and CIBERehd are initiatives of the Instituto de Salud Carlos III (ISCIII) of Spain which is supported by FEDER funds. We thank MINECO for the Severo Ochoa Excellence Accreditation to CIC bioGUNE (SEV-2016-0644).

UN SDGs

Dieser Output leistet einen Beitrag zu folgendem(n) Ziel(en) für nachhaltige Entwicklung

SDG 3 – Gesundheit und Wohlergehen

Strategische Forschungsbereiche und Zentren

Forschungsschwerpunkt: Gehirn, Hormone, Verhalten - Center for Brain, Behavior and Metabolism (CBBM)

Coronavirus-Bezug

Forschung zu SARS-CoV-2 / COVID-19

Dokumente

10.1016/j.jhep.2020.09.027

Weitere Links

Zitieren

Fondevila, M. F., Mercado-Gómez, M., Rodríguez, A., Gonzalez-Rellan, M. J., Iruzubieta, P., Valentí, V., Escalada, J., Schwaninger, M., Prevot, V., Dieguez, C., Crespo, J., Frühbeck, G., Martinez-Chantar, M. L., & Nogueiras, R. (2021). Obese patients with NASH have increased hepatic expression of SARS-CoV-2 critical entry points. Journal of Hepatology, 74(2), 469-471. https://doi.org/10.1016/j.jhep.2020.09.027

@article{de8e4f78291b4b489774d5d0a5552ec2,

title = "Obese patients with NASH have increased hepatic expression of SARS-CoV-2 critical entry points",

author = "Fondevila, \{Marcos F.\} and Maria Mercado-G{\'o}mez and Amaia Rodr{\'i}guez and Gonzalez-Rellan, \{Maria J.\} and Paula Iruzubieta and V{\'i}ctor Valent{\'i} and Javier Escalada and Markus Schwaninger and Vincent Prevot and Carlos Dieguez and Javier Crespo and Gema Fr{\"u}hbeck and Martinez-Chantar, \{Maria L.\} and Ruben Nogueiras",

note = "Funding Information: This work has been supported by grants from FEDER/Ministerio de Ciencia, Innovaci?n y Universidades-Agencia Estatal de Investigaci?n (CD: BFU2017-87721; RN: RTI2018-099413-B-I00; MLMC: SAF2017-87301-R; Xunta de Galicia (RN: 2015-CP080 and 2016-PG057) and ED431G 2019/02, Fundaci?n BBVA (RN and MLM), Fundaci?n Atresmedia (RN), and European Foundation for the Study of Diabetes (RN). FIS: PI18/0130. Immunomediatd Nonalcoholic SteaTohepatItis; prevalence and CharacTerization. INSTInCT study (PI: Javier Crespo). Intensificaci?n IDIVAL I-1 (Javier Crespo). The research leading to these results has also received funding from the European Community's H2020 Framework Programme under the following grant: ERC Synergy Grant-2019-WATCH- 810331 to MS, VP and RN. CIBERobn and CIBERehd are initiatives of the Instituto de Salud Carlos III (ISCIII) of Spain which is supported by FEDER funds. We thank MINECO for the Severo Ochoa Excellence Accreditation to CIC bioGUNE (SEV-2016-0644). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",

year = "2021",

month = feb,

doi = "10.1016/j.jhep.2020.09.027",

language = "English",

volume = "74",

pages = "469--471",

journal = "Journal of Hepatology",

issn = "0168-8278",

publisher = "Elsevier B.V.",

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}

Fondevila, MF, Mercado-Gómez, M, Rodríguez, A, Gonzalez-Rellan, MJ, Iruzubieta, P, Valentí, V, Escalada, J, Schwaninger, M, Prevot, V, Dieguez, C, Crespo, J, Frühbeck, G, Martinez-Chantar, ML & Nogueiras, R 2021, 'Obese patients with NASH have increased hepatic expression of SARS-CoV-2 critical entry points', Journal of Hepatology, Jg. 74, Nr. 2, S. 469-471. https://doi.org/10.1016/j.jhep.2020.09.027

TY - JOUR

T1 - Obese patients with NASH have increased hepatic expression of SARS-CoV-2 critical entry points

AU - Fondevila, Marcos F.

AU - Mercado-Gómez, Maria

AU - Rodríguez, Amaia

AU - Gonzalez-Rellan, Maria J.

AU - Iruzubieta, Paula

AU - Valentí, Víctor

AU - Escalada, Javier

AU - Schwaninger, Markus

AU - Prevot, Vincent

AU - Dieguez, Carlos

AU - Crespo, Javier

AU - Frühbeck, Gema

AU - Martinez-Chantar, Maria L.

AU - Nogueiras, Ruben

N1 - Funding Information: This work has been supported by grants from FEDER/Ministerio de Ciencia, Innovaci?n y Universidades-Agencia Estatal de Investigaci?n (CD: BFU2017-87721; RN: RTI2018-099413-B-I00; MLMC: SAF2017-87301-R; Xunta de Galicia (RN: 2015-CP080 and 2016-PG057) and ED431G 2019/02, Fundaci?n BBVA (RN and MLM), Fundaci?n Atresmedia (RN), and European Foundation for the Study of Diabetes (RN). FIS: PI18/0130. Immunomediatd Nonalcoholic SteaTohepatItis; prevalence and CharacTerization. INSTInCT study (PI: Javier Crespo). Intensificaci?n IDIVAL I-1 (Javier Crespo). The research leading to these results has also received funding from the European Community's H2020 Framework Programme under the following grant: ERC Synergy Grant-2019-WATCH- 810331 to MS, VP and RN. CIBERobn and CIBERehd are initiatives of the Instituto de Salud Carlos III (ISCIII) of Spain which is supported by FEDER funds. We thank MINECO for the Severo Ochoa Excellence Accreditation to CIC bioGUNE (SEV-2016-0644). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2021/2

Y1 - 2021/2

UR - https://www.scopus.com/pages/publications/85097384624

UR - https://www.mendeley.com/catalogue/b59ed5db-891a-32e5-b379-462ea30605eb/

U2 - 10.1016/j.jhep.2020.09.027

DO - 10.1016/j.jhep.2020.09.027

M3 - Letters

C2 - 33096086

AN - SCOPUS:85097384624

SN - 0168-8278

VL - 74

SP - 469

EP - 471

JO - Journal of Hepatology

JF - Journal of Hepatology

IS - 2

ER -