Modelling of a Bi-Modal PET / Compton-Camera System for Non-Pure Positron Emitters

A. Bolke; M. Zvolsky; N. Kohlhase; S. Seeger; M. Schaar; Magdalena Rafecas

doi:10.1109/NSS/MIC42677.2020.9507915

Modelling of a Bi-Modal PET / Compton-Camera System for Non-Pure Positron Emitters

A. Bolke, M. Zvolsky, N. Kohlhase, S. Seeger, M. Schaar, Magdalena Rafecas

Institut für Medizintechnik

Abstract

In this work, we investigate the combination of two imaging modalities, positron emission tomography (PET) and Compton-camera (CC) imaging. A prototype for simultaneous PET/CC acquisition was simulated. The design is based on the combination of two existing prototypes and allows for a first investigation of the bi-modal acquisition of the radionuclides 89Zr and 124I. Since the simulation framework GATE is not able to properly output coincidences of such a bi-modal system, a post-processing tool was developed. This includes custom coincidence sorting and classification of PET and CC data. Here we present our postprocessing pipeline as well as our first results, and discuss the implications of the coincidence logic and the fraction of randoms on the data. The availability of such data is the prerequisite for developing novel image reconstruction approaches.

Originalsprache	Englisch
Titel	2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)
Seitenumfang	3
Herausgeber (Verlag)	IEEE
Erscheinungsdatum	11.2020
Seiten	1-3
ISBN (Print)	978-1-7281-7694-9
ISBN (elektronisch)	978-1-7281-7693-2
DOIs	https://doi.org/10.1109/NSS/MIC42677.2020.9507915
Publikationsstatus	Veröffentlicht - 11.2020

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title = "Modelling of a Bi-Modal PET / Compton-Camera System for Non-Pure Positron Emitters",

abstract = "In this work, we investigate the combination of two imaging modalities, positron emission tomography (PET) and Compton-camera (CC) imaging. A prototype for simultaneous PET/CC acquisition was simulated. The design is based on the combination of two existing prototypes and allows for a first investigation of the bi-modal acquisition of the radionuclides 89Zr and 124I. Since the simulation framework GATE is not able to properly output coincidences of such a bi-modal system, a post-processing tool was developed. This includes custom coincidence sorting and classification of PET and CC data. Here we present our postprocessing pipeline as well as our first results, and discuss the implications of the coincidence logic and the fraction of randoms on the data. The availability of such data is the prerequisite for developing novel image reconstruction approaches.",

author = "A. Bolke and M. Zvolsky and N. Kohlhase and S. Seeger and M. Schaar and Magdalena Rafecas",

year = "2020",

month = nov,

doi = "10.1109/NSS/MIC42677.2020.9507915",

language = "English",

isbn = "978-1-7281-7694-9",

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booktitle = "2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)",

publisher = "IEEE",

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TY - GEN

T1 - Modelling of a Bi-Modal PET / Compton-Camera System for Non-Pure Positron Emitters

AU - Bolke, A.

AU - Zvolsky, M.

AU - Kohlhase, N.

AU - Seeger, S.

AU - Schaar, M.

AU - Rafecas, Magdalena

PY - 2020/11

Y1 - 2020/11

N2 - In this work, we investigate the combination of two imaging modalities, positron emission tomography (PET) and Compton-camera (CC) imaging. A prototype for simultaneous PET/CC acquisition was simulated. The design is based on the combination of two existing prototypes and allows for a first investigation of the bi-modal acquisition of the radionuclides 89Zr and 124I. Since the simulation framework GATE is not able to properly output coincidences of such a bi-modal system, a post-processing tool was developed. This includes custom coincidence sorting and classification of PET and CC data. Here we present our postprocessing pipeline as well as our first results, and discuss the implications of the coincidence logic and the fraction of randoms on the data. The availability of such data is the prerequisite for developing novel image reconstruction approaches.

AB - In this work, we investigate the combination of two imaging modalities, positron emission tomography (PET) and Compton-camera (CC) imaging. A prototype for simultaneous PET/CC acquisition was simulated. The design is based on the combination of two existing prototypes and allows for a first investigation of the bi-modal acquisition of the radionuclides 89Zr and 124I. Since the simulation framework GATE is not able to properly output coincidences of such a bi-modal system, a post-processing tool was developed. This includes custom coincidence sorting and classification of PET and CC data. Here we present our postprocessing pipeline as well as our first results, and discuss the implications of the coincidence logic and the fraction of randoms on the data. The availability of such data is the prerequisite for developing novel image reconstruction approaches.

UR - https://ieeexplore.ieee.org/document/9507915

U2 - 10.1109/NSS/MIC42677.2020.9507915

DO - 10.1109/NSS/MIC42677.2020.9507915

M3 - Conference contribution

SN - 978-1-7281-7694-9

SP - 1

EP - 3

BT - 2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)

PB - IEEE

ER -

Modelling of a Bi-Modal PET / Compton-Camera System for Non-Pure Positron Emitters

Abstract

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