Metabolic syndrome in patients with myotonic dystrophy type 1

Milorad Vujnic, Stojan Peric*, Srdjan Popovic, Nela Raseta, Vesna Ralic, Valerija Dobricic, Ivana Novakovic, Vidosava Rakocevic-Stojanovic

*Korrespondierende/r Autor/-in für diese Arbeit
19 Zitate (Scopus)

Abstract

Introduction: The aim of this study was to assess the frequency and features of metabolic syndrome (MetS) in myotonic dystrophy type 1 (DM1). Methods: We studied 66 DM1 patients (50% men, aged 41.9±10.5 years, disease duration of 19.3±8.6 years). New worldwide consensus criteria for MetS from 2009 were used. Results: Components of MetS were present at the following frequencies: hypertriglyceridemia 67%; low HDL cholesterol 35%; hypertension 18%; central obesity 14%; and hyperglycemia 9%. MetS was present in 11 (17%) patients. The presence of MetS was not associated with patients' gender, age, disease severity, disease duration, or CTG repeat length (P>0.05). Patients with MetS had significantly lower total SF-36 scores as a measure of quality of life in comparison to patients without MetS (P<0.05). Conclusion: Although certain components of MetS were very frequent in patients with DM1, only 17% met the criteria for MetS.

OriginalspracheEnglisch
ZeitschriftMuscle and Nerve
Jahrgang52
Ausgabenummer2
Seiten (von - bis)273-277
Seitenumfang5
ISSN0148-639X
DOIs
PublikationsstatusVeröffentlicht - 01.08.2015

Fingerprint

Untersuchen Sie die Forschungsthemen von „Metabolic syndrome in patients with myotonic dystrophy type 1“. Zusammen bilden sie einen einzigartigen Fingerprint.

Zitieren