Massive weight loss following deep brain stimulation of the nucleus accumbens in a depressed woman

Volker M Tronnier; Dirk Rasche; Veronika Thorns; Daniel Alvarez-Fischer; Thomas F Münte; Bartosz Zurowski

doi:10.1080/13554794.2018.1431678

Massive weight loss following deep brain stimulation of the nucleus accumbens in a depressed woman

Volker M Tronnier, Dirk Rasche, Veronika Thorns, Daniel Alvarez-Fischer, Thomas F Münte, Bartosz Zurowski

Abstract

Obese individuals share behavioral characteristics with drug/alcohol addicts as well as obsessive compulsive disease. Deep brain stimulation (DBS) has been used successfully in these disorders, thus warranting an evaluation in obesity. A woman with treatment-resistant depression as well as severe obesity was selected for DBS of the nucleus accumbens (NAcc) bilaterally with depression being the primary and obesity being the secondary target of treatment. Compared to earlier bariatric surgery, the patient showed accelerated weight loss after DBS. Also, depression was significantly reduced. The current case suggests that DBS of the NAcc warrants further evaluation in patients unresponsive to other treatments.

Originalsprache	Englisch
Zeitschrift	Neurocase : case studies in neuropsychology, neuropsychiatry, and behavioural neurology
Jahrgang	24
Ausgabenummer	1
Seiten (von - bis)	49-53
Seitenumfang	5
ISSN	1355-4794
DOIs	https://doi.org/10.1080/13554794.2018.1431678
Publikationsstatus	Veröffentlicht - 02.2018

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10.1080/13554794.2018.1431678

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abstract = "Obese individuals share behavioral characteristics with drug/alcohol addicts as well as obsessive compulsive disease. Deep brain stimulation (DBS) has been used successfully in these disorders, thus warranting an evaluation in obesity. A woman with treatment-resistant depression as well as severe obesity was selected for DBS of the nucleus accumbens (NAcc) bilaterally with depression being the primary and obesity being the secondary target of treatment. Compared to earlier bariatric surgery, the patient showed accelerated weight loss after DBS. Also, depression was significantly reduced. The current case suggests that DBS of the NAcc warrants further evaluation in patients unresponsive to other treatments.",

author = "Tronnier, \{Volker M\} and Dirk Rasche and Veronika Thorns and Daniel Alvarez-Fischer and M{\"u}nte, \{Thomas F\} and Bartosz Zurowski",

year = "2018",

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doi = "10.1080/13554794.2018.1431678",

language = "English",

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Massive weight loss following deep brain stimulation of the nucleus accumbens in a depressed woman. / Tronnier, Volker M ; Rasche, Dirk; Thorns, Veronika et al.
in: Neurocase : case studies in neuropsychology, neuropsychiatry, and behavioural neurology, Jahrgang 24, Nr. 1, 02.2018, S. 49-53.

Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

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T1 - Massive weight loss following deep brain stimulation of the nucleus accumbens in a depressed woman

AU - Tronnier, Volker M

AU - Rasche, Dirk

AU - Thorns, Veronika

AU - Alvarez-Fischer, Daniel

AU - Münte, Thomas F

AU - Zurowski, Bartosz

PY - 2018/2

Y1 - 2018/2

N2 - Obese individuals share behavioral characteristics with drug/alcohol addicts as well as obsessive compulsive disease. Deep brain stimulation (DBS) has been used successfully in these disorders, thus warranting an evaluation in obesity. A woman with treatment-resistant depression as well as severe obesity was selected for DBS of the nucleus accumbens (NAcc) bilaterally with depression being the primary and obesity being the secondary target of treatment. Compared to earlier bariatric surgery, the patient showed accelerated weight loss after DBS. Also, depression was significantly reduced. The current case suggests that DBS of the NAcc warrants further evaluation in patients unresponsive to other treatments.

AB - Obese individuals share behavioral characteristics with drug/alcohol addicts as well as obsessive compulsive disease. Deep brain stimulation (DBS) has been used successfully in these disorders, thus warranting an evaluation in obesity. A woman with treatment-resistant depression as well as severe obesity was selected for DBS of the nucleus accumbens (NAcc) bilaterally with depression being the primary and obesity being the secondary target of treatment. Compared to earlier bariatric surgery, the patient showed accelerated weight loss after DBS. Also, depression was significantly reduced. The current case suggests that DBS of the NAcc warrants further evaluation in patients unresponsive to other treatments.

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DO - 10.1080/13554794.2018.1431678

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JO - Neurocase : case studies in neuropsychology, neuropsychiatry, and behavioural neurology

JF - Neurocase : case studies in neuropsychology, neuropsychiatry, and behavioural neurology

IS - 1

ER -

Massive weight loss following deep brain stimulation of the nucleus accumbens in a depressed woman

Abstract

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