Lectin-dependent cellular cytotoxicity by human lymphocytes is blocked by monoclonal antibodies to the sheep red cell receptor

György Görög; Tamás Laskay; G. Petrányi

doi:10.1016/0165-2478(85)90151-8

Lectin-dependent cellular cytotoxicity by human lymphocytes is blocked by monoclonal antibodies to the sheep red cell receptor

György Görög^*, Tamás Laskay, G. Petrányi

^*Korrespondierende/r Autor/-in für diese Arbeit

Klinik für Infektiologie und Mikrobiologie

National Institute of Haematology and Blood Transfusion Budapest

3 Zitate (Scopus)

Abstract

Investigating the functional effects of anti-T cell monoclonal antibodies (obtained through the Second International Workshop on Human Leucocyte Differentiation Antigens), antibodies to the sheep red cell receptor (CD2) were found to block lectin-dependent cytotoxicity. Blocking was seen with all anti-CD2 reagents tested regardless of epitope specificity, immunoglobulin subclass or other factors. Antibodies to other T cell differentiation antigens had no effect.

Originalsprache	Englisch
Zeitschrift	Immunology Letters
Jahrgang	11
Ausgabenummer	2
Seiten (von - bis)	107-109
Seitenumfang	3
ISSN	0165-2478
DOIs	https://doi.org/10.1016/0165-2478(85)90151-8
Publikationsstatus	Veröffentlicht - 01.01.1985

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Forschungsschwerpunkt: Infektion und Entzündung - Zentrum für Infektions- und Entzündungsforschung Lübeck (ZIEL)

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10.1016/0165-2478(85)90151-8

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abstract = "Investigating the functional effects of anti-T cell monoclonal antibodies (obtained through the Second International Workshop on Human Leucocyte Differentiation Antigens), antibodies to the sheep red cell receptor (CD2) were found to block lectin-dependent cytotoxicity. Blocking was seen with all anti-CD2 reagents tested regardless of epitope specificity, immunoglobulin subclass or other factors. Antibodies to other T cell differentiation antigens had no effect.",

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AU - Görög, György

AU - Laskay, Tamás

AU - Petrányi, G.

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Y1 - 1985/1/1

N2 - Investigating the functional effects of anti-T cell monoclonal antibodies (obtained through the Second International Workshop on Human Leucocyte Differentiation Antigens), antibodies to the sheep red cell receptor (CD2) were found to block lectin-dependent cytotoxicity. Blocking was seen with all anti-CD2 reagents tested regardless of epitope specificity, immunoglobulin subclass or other factors. Antibodies to other T cell differentiation antigens had no effect.

AB - Investigating the functional effects of anti-T cell monoclonal antibodies (obtained through the Second International Workshop on Human Leucocyte Differentiation Antigens), antibodies to the sheep red cell receptor (CD2) were found to block lectin-dependent cytotoxicity. Blocking was seen with all anti-CD2 reagents tested regardless of epitope specificity, immunoglobulin subclass or other factors. Antibodies to other T cell differentiation antigens had no effect.

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Lectin-dependent cellular cytotoxicity by human lymphocytes is blocked by monoclonal antibodies to the sheep red cell receptor

Abstract

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