Karnofsky performance score is predictive of survival after palliative irradiation of metastatic bile duct cancer

Dirk Rades*, Louisa Bolm, Lukas Kaesmann, Tobias Bartscht

*Korrespondierende/r Autor/-in für diese Arbeit
1 Zitat (Scopus)

Abstract

Background/Aim: Palliative irradiation is effective in alleviating symptoms in patients with metastatic cancer in general. However, little data exist regarding irradiation of metastatic bile duct cancer. Selection of the best regimen for such a patient should be based on their survival prognosis. Patients and Methods: This study included five patients irradiated for metastatic bile duct cancer and aimed to identify predictors of survival by analyzing six factors: age, gender, general condition (Karnofsky performance score), metastatic site receiving palliative irradiation, metastases outside irradiated sites and time between diagnosis of bile duct cancer and palliative irradiation. Results: In the whole series, median survival was 3 months. Survival rates at 3 and 6 months were 40% and 40%, respectively. A Karnofsky performance score >70% had a borderline significant association with better survival (p=0.05). Conclusion: Karnofsky performance score was identified as predictor of survival and should be considered when assigning the radiation regimen to patients with metastatic bile duct cancer.

OriginalspracheEnglisch
ZeitschriftAnticancer Research
Jahrgang37
Ausgabenummer2
Seiten (von - bis)949-952
Seitenumfang4
ISSN0250-7005
PublikationsstatusVeröffentlicht - 2017

Strategische Forschungsbereiche und Zentren

  • Forschungsschwerpunkt: Gehirn, Hormone, Verhalten - Center for Brain, Behavior and Metabolism (CBBM)

Fingerprint

Untersuchen Sie die Forschungsthemen von „Karnofsky performance score is predictive of survival after palliative irradiation of metastatic bile duct cancer“. Zusammen bilden sie einen einzigartigen Fingerprint.

Zitieren