Interferometric detection of laser induced microbubbles in the retinal pigment epithelium

Jörg Neumann; Ralf Brinkmann

doi:10.1117/12.446505

Interferometric detection of laser induced microbubbles in the retinal pigment epithelium

Jörg Neumann^*, Ralf Brinkmann

^*Korrespondierende/r Autor/-in für diese Arbeit

Institut für Biomedizinische Optik

Abstract

We developed an interferometric technique in order to detect microbubble formation within porcine retinal pigment epithelial (RPE) cells ex vivo after short pulsed laser exposure (527 nm, 350 ns). The irradiated surface of the RPE tissue samples was monitored by a Michelson interferometer. The obtained interferometric transients revealed bubble dynamics and were compared to optoacoustic transients recorded simultaneously. This interferometric technique might be useful for in vivo dosimetry during selective RPE-treatment.

Originalsprache	Englisch
Zeitschrift	Proceedings of SPIE - The International Society for Optical Engineering
Jahrgang	4433
Seiten (von - bis)	81-86
Seitenumfang	6
ISSN	0277-786X
DOIs	https://doi.org/10.1117/12.446505
Publikationsstatus	Veröffentlicht - 26.10.2001
Veranstaltung	Laser-Tissue Interactions, Therapeutic Applications, and Photodynamic Therapy 2001 - Munich, Deutschland Dauer: 18.06.2001 → 21.06.2001 Konferenznummer: 59925

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Forschungsschwerpunkt: Biomedizintechnik

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abstract = "We developed an interferometric technique in order to detect microbubble formation within porcine retinal pigment epithelial (RPE) cells ex vivo after short pulsed laser exposure (527 nm, 350 ns). The irradiated surface of the RPE tissue samples was monitored by a Michelson interferometer. The obtained interferometric transients revealed bubble dynamics and were compared to optoacoustic transients recorded simultaneously. This interferometric technique might be useful for in vivo dosimetry during selective RPE-treatment.",

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JO - Proceedings of SPIE - The International Society for Optical Engineering

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Interferometric detection of laser induced microbubbles in the retinal pigment epithelium

Abstract

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