Inter-reader variability in chest radiography and HRCT for the early detection of asbestos-related lung and pleural abnormalities in a cohort of 636 asbestos-exposed subjects

Elke Ochsmann*, Tanja Carl, Peter Brand, Hans Jürgen Raithel, Thomas Kraus

*Korrespondierende/r Autor/-in für diese Arbeit
24 Zitate (Scopus)

Abstract

Purpose To compare inter-reader variability of chest X-ray and high resolution computed tomography (HRCT) scans of formerly asbestos-exposed employees over a 4-year period. Methods In this longitudinal study, 636 formerly asbestos-exposed persons were annually examined with chest radiographs and HRCT scans. Ten observer pairs classified the radiographs and HRCT scans, using the ILO classification and a custom-made CT classification. Inter-observer variability was calculated using the K-coefficient. Results Despite all expectations, HRCT inter-reader variability according to asbestos-related lung or pleura alterations at an early stage did not turn out to be better than X-ray inter-reader variability. Substantial inter-observer agreement was found for pleural calcifications (KX-ray = 0.63; KCT = 0.64). Averaging over K led to fair inter-observer agreement of both methods (K X-ray = 0.36; KCT = 0.34). Conclusions High resolution computed tomography scans are superior to X-rays in detecting lung alterations after asbestos exposure and are supposedly easier to interpret. Nevertheless, inter-observer variability did not differ between the two methods in this study. This was probably due to the only discrete asbestos-related lung or pleura alterations of this cohort and to the unfamiliar CT classification sheet, which was revised on the basis of the presented results.

OriginalspracheEnglisch
ZeitschriftInternational Archives of Occupational and Environmental Health
Jahrgang83
Ausgabenummer1
Seiten (von - bis)39-46
Seitenumfang8
ISSN0340-0131
DOIs
PublikationsstatusVeröffentlicht - 01.01.2010

DFG-Fachsystematik

  • 205-10 Toxikologie, Arbeitsmedizin, Klinische Chemie

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