Infektionen nach Organtransplantation

Potent immunosuppressive therapies increased the rate of successful solid organ transplantations, but are also associated with augmented risk for infections. The pathogens can originate from the pretransplant period (endogenous reactivation), donor-derived, or newly acquired. Immunosuppression can disguise infection by mild clinical symptoms and atypical laboratory constellation. Therefore, it is important to consider early in the process a systematic diagnostic workflow including rare pathogens which are sometimes not detectable by routine methods.