Abstract
Transcription is an energy-consuming process. From an economical view it is reasonable that not all genes are transcribed simultaneously in one cell. Indeed, most genes are transcribed only when a specific gene product is needed. Regulation of gene expression is mainly achieved by the coordinate interplay of different transcription factors (TFs) and transcriptional coactivators with DNA-dependent RNA-polymerases. To gain spatial and temporal control in this process, TFs have to fulfill two prerequisites: sequence specificity and inducibility.
Originalsprache | Englisch |
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Titel | Oxygen Sensing : Responses and Adaption to Hypoxia |
Seitenumfang | 16 |
Herausgeber (Verlag) | CRC Press |
Erscheinungsdatum | 01.01.2003 |
Seiten | 93-108 |
ISBN (Print) | 9780824709600 |
ISBN (elektronisch) | 9780824748456 |
Publikationsstatus | Veröffentlicht - 01.01.2003 |
Strategische Forschungsbereiche und Zentren
- Forschungsschwerpunkt: Gehirn, Hormone, Verhalten - Center for Brain, Behavior and Metabolism (CBBM)