Hypopituitarism in a HIV affected patient

B. Harbeck*, S. Klose, M. Buchfelder, G. Brabant, H. Lehnert

*Korrespondierende/r Autor/-in für diese Arbeit
6 Zitate (Scopus)

Abstract

Background: The clinical picture of pituitary abscesses may resemble features of other pituitary pathologies including endocrine deficiencies. The characteristic radiological changes, namely the ring enhancement, may aid in the diagnostic work-up of this very rare condition. Case Report: A 40-year-old patient with longstanding HIV infection presented with headache and fatigue. Testing for pituitary function confirmed panhypopitutarism. MRI scanning demonstrated an inhomogeneous pituitary gland with ring-like enhancement and sphenoid sinus mucosa thickening. Transsphenoidal surgery was performed. Histologically CD68 positive macrophages were found supporting the diagnosis of infectious hypophysitis. Under hormone replacement therapy and retroviral treatment the patient clinically normalized. Conclusion: A pituitary abscess due to infectious hypophysitis is a rare cause of pituitary failure. Diagnostic signs on imaging may help to rapidly distinguish the cause of pituitary deficiency in patients with HIV infection.

OriginalspracheEnglisch
ZeitschriftExperimental and Clinical Endocrinology and Diabetes
Jahrgang119
Ausgabenummer10
Seiten (von - bis)633-635
Seitenumfang3
ISSN0947-7349
DOIs
PublikationsstatusVeröffentlicht - 19.09.2011

DFG-Fachsystematik

  • 205-31 Klinische Infektiologie und Tropenmedizin

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