Histopathological features and ann arbor stage in periocular lymphoma

Marco Zschoche; Annette Zimpfer; Björn O. Scheef; Anselm M. Jünemann; Rudolf F. Guthoff; Christian Junghanss; Guido Hildebrandt; Steffen Emmert; Andreas Erbersdobler; Günther Kundt; Vinodh Kakkassery

doi:10.21873/invivo.11993

Histopathological features and ann arbor stage in periocular lymphoma

Marco Zschoche^*, Annette Zimpfer, Björn O. Scheef, Anselm M. Jünemann, Rudolf F. Guthoff, Christian Junghanss, Guido Hildebrandt, Steffen Emmert, Andreas Erbersdobler, Günther Kundt, Vinodh Kakkassery

^*Korrespondierende/r Autor/-in für diese Arbeit

Klinik für Augenheilkunde

Universität Rostock

12 Zitate (Scopus)

Abstract

Background: To evaluate biodata, symptoms/signs, lymphoma type, localization, stage level, treatment choice and outcome of ocular adnexal lymphoma (OAL). Patients and Methods: A single-center retrospective analysis of 56 patients with OAL was performed from 1998 to 2018. Results: OAL involved the orbit in 44.6%, the conjunctiva in 32.1%, the lacrimal apparatus in 14.3% and the eyelid in 8.93%. Extranodal marginal zone B-cell lymphoma (EMZL) was found in 60.7%, follicular lymphoma (FL) in 21.4%, diffuse large Bcell lymphoma in 7.14%, mantle cell lymphoma in 5.36% and chronic lymphatic leukaemia in 5.36% patients. No relapse was seen in 76%. EMZL and FL had a significantly better overall survival compared to other lymphoma types (p=0.002). Patients with Ann Arbor stage IE had a significantly better prognosis than those with stages higher than IE (p=0.048). Conclusion: Our data suggest that clinicopathological features such as Ann Arbor stage influence survival.

Originalsprache	Englisch
Zeitschrift	In Vivo
Jahrgang	34
Ausgabenummer	4
Seiten (von - bis)	1965-1974
Seitenumfang	10
ISSN	0258-851X
DOIs	https://doi.org/10.21873/invivo.11993
Publikationsstatus	Veröffentlicht - 08.2020

Fördermittel

S.E. is supported by the European Social Fund, reference: ESF/14-BM-A55-0001/18, and the Ministry of Education, Science and Culture of Mecklenburg-West Pomerania, Germany as well as by the Damp Foundation.

UN SDGs

Dieser Output leistet einen Beitrag zu folgendem(n) Ziel(en) für nachhaltige Entwicklung

SDG 3 – Gesundheit und Wohlergehen
SDG 9 – Industrie, Innovation und Infrastruktur

Strategische Forschungsbereiche und Zentren

Profilbereich: Lübeck Integrated Oncology Network (LION)

Dokumente

10.21873/invivo.11993

Weitere Links

Link to publication in Scopus

Zitieren

@article{73fd42c282c9449fb097fc0c3496f7dd,

title = "Histopathological features and ann arbor stage in periocular lymphoma",

abstract = "Background: To evaluate biodata, symptoms/signs, lymphoma type, localization, stage level, treatment choice and outcome of ocular adnexal lymphoma (OAL). Patients and Methods: A single-center retrospective analysis of 56 patients with OAL was performed from 1998 to 2018. Results: OAL involved the orbit in 44.6\%, the conjunctiva in 32.1\%, the lacrimal apparatus in 14.3\% and the eyelid in 8.93\%. Extranodal marginal zone B-cell lymphoma (EMZL) was found in 60.7\%, follicular lymphoma (FL) in 21.4\%, diffuse large Bcell lymphoma in 7.14\%, mantle cell lymphoma in 5.36\% and chronic lymphatic leukaemia in 5.36\% patients. No relapse was seen in 76\%. EMZL and FL had a significantly better overall survival compared to other lymphoma types (p=0.002). Patients with Ann Arbor stage IE had a significantly better prognosis than those with stages higher than IE (p=0.048). Conclusion: Our data suggest that clinicopathological features such as Ann Arbor stage influence survival.",

author = "Marco Zschoche and Annette Zimpfer and Scheef, \{Bj{\"o}rn O.\} and J{\"u}nemann, \{Anselm M.\} and Guthoff, \{Rudolf F.\} and Christian Junghanss and Guido Hildebrandt and Steffen Emmert and Andreas Erbersdobler and G{\"u}nther Kundt and Vinodh Kakkassery",

note = "Funding Information: S.E. is supported by the European Social Fund, reference: ESF/14-BM-A55-0001/18, and the Ministry of Education, Science and Culture of Mecklenburg-West Pomerania, Germany as well as by the Damp Foundation. Publisher Copyright: {\textcopyright} 2020 International Institute of Anticancer Research. All rights reserved. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",

year = "2020",

month = aug,

doi = "10.21873/invivo.11993",

language = "English",

volume = "34",

pages = "1965--1974",

journal = "In Vivo",

issn = "0258-851X",

publisher = "International Institute of Anticancer Research",

number = "4",

}

TY - JOUR

T1 - Histopathological features and ann arbor stage in periocular lymphoma

AU - Zschoche, Marco

AU - Zimpfer, Annette

AU - Scheef, Björn O.

AU - Jünemann, Anselm M.

AU - Guthoff, Rudolf F.

AU - Junghanss, Christian

AU - Hildebrandt, Guido

AU - Emmert, Steffen

AU - Erbersdobler, Andreas

AU - Kundt, Günther

AU - Kakkassery, Vinodh

N1 - Funding Information: S.E. is supported by the European Social Fund, reference: ESF/14-BM-A55-0001/18, and the Ministry of Education, Science and Culture of Mecklenburg-West Pomerania, Germany as well as by the Damp Foundation. Publisher Copyright: © 2020 International Institute of Anticancer Research. All rights reserved. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2020/8

Y1 - 2020/8

N2 - Background: To evaluate biodata, symptoms/signs, lymphoma type, localization, stage level, treatment choice and outcome of ocular adnexal lymphoma (OAL). Patients and Methods: A single-center retrospective analysis of 56 patients with OAL was performed from 1998 to 2018. Results: OAL involved the orbit in 44.6%, the conjunctiva in 32.1%, the lacrimal apparatus in 14.3% and the eyelid in 8.93%. Extranodal marginal zone B-cell lymphoma (EMZL) was found in 60.7%, follicular lymphoma (FL) in 21.4%, diffuse large Bcell lymphoma in 7.14%, mantle cell lymphoma in 5.36% and chronic lymphatic leukaemia in 5.36% patients. No relapse was seen in 76%. EMZL and FL had a significantly better overall survival compared to other lymphoma types (p=0.002). Patients with Ann Arbor stage IE had a significantly better prognosis than those with stages higher than IE (p=0.048). Conclusion: Our data suggest that clinicopathological features such as Ann Arbor stage influence survival.

AB - Background: To evaluate biodata, symptoms/signs, lymphoma type, localization, stage level, treatment choice and outcome of ocular adnexal lymphoma (OAL). Patients and Methods: A single-center retrospective analysis of 56 patients with OAL was performed from 1998 to 2018. Results: OAL involved the orbit in 44.6%, the conjunctiva in 32.1%, the lacrimal apparatus in 14.3% and the eyelid in 8.93%. Extranodal marginal zone B-cell lymphoma (EMZL) was found in 60.7%, follicular lymphoma (FL) in 21.4%, diffuse large Bcell lymphoma in 7.14%, mantle cell lymphoma in 5.36% and chronic lymphatic leukaemia in 5.36% patients. No relapse was seen in 76%. EMZL and FL had a significantly better overall survival compared to other lymphoma types (p=0.002). Patients with Ann Arbor stage IE had a significantly better prognosis than those with stages higher than IE (p=0.048). Conclusion: Our data suggest that clinicopathological features such as Ann Arbor stage influence survival.

UR - https://www.scopus.com/pages/publications/85087384389

U2 - 10.21873/invivo.11993

DO - 10.21873/invivo.11993

M3 - Journal articles

C2 - 32606168

AN - SCOPUS:85087384389

SN - 0258-851X

VL - 34

SP - 1965

EP - 1974

JO - In Vivo

JF - In Vivo

IS - 4

ER -

Histopathological features and ann arbor stage in periocular lymphoma

Abstract

Fördermittel

UN SDGs

Strategische Forschungsbereiche und Zentren

Dokumente

Weitere Links

Fingerprint

Zitieren