Helium‐Neon laser irradiation inhibits the growth of kidney epithelial cells in culture

Andreas J. Gross, Wolfgang Jelkmann*

*Korrespondierende/r Autor/-in für diese Arbeit
40 Zitate (Scopus)

Abstract

We have investigated the in vitro action of helium‐neon (He‐Ne) laser light on the cell cycle and the growth of rat kidney epithelial cell cultures. Dose‐response studies showed that repeated He‐Ne irradiation (dose rate 40 mW/cm2) once a day in a dose range between 11.9 and 142 J/cm2 significantly inhibited cell growth, while daily irradiation with 4.7 J/cm2 had no effect. Microscopic examination of nuclear spreads revealed an increased number of cells in mitosis after a single irradiation with 142 J/cm2. These results support previous observations suggesting that laser light of low thermal energy interferes with cell cycling and may inhibit cell growth when irradiation is performed at doses of 11.9 J/cm2 or more.

OriginalspracheEnglisch
ZeitschriftLasers in Surgery and Medicine
Jahrgang10
Ausgabenummer1
Seiten (von - bis)40-44
Seitenumfang5
ISSN0196-8092
DOIs
PublikationsstatusVeröffentlicht - 1990

Strategische Forschungsbereiche und Zentren

  • Forschungsschwerpunkt: Gehirn, Hormone, Verhalten - Center for Brain, Behavior and Metabolism (CBBM)

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