Ghrelin

T. D. Müller; R. Nogueiras; M. L. Andermann; Z. B. Andrews; S. D. Anker; J. Argente; R. L. Batterham; S. C. Benoit; C. Y. Bowers; F. Broglio; F. F. Casanueva; D. D'Alessio; I. Depoortere; A. Geliebter; E. Ghigo; P. A. Cole; M. Cowley; D. E. Cummings; A. Dagher; S. Diano; S. L. Dickson; C. Diéguez; R. Granata; H. J. Grill; K. Grove; K. M. Habegger; K. Heppner; M. L. Heiman; L. Holsen; B. Holst; A. Inui; J. O. Jansson; H. Kirchner; M. Korbonits; B. Laferrère; C. W. LeRoux; M. Lopez; S. Morin; M. Nakazato; R. Nass; D. Perez-Tilve; P. T. Pfluger; T. W. Schwartz; R. J. Seeley; M. Sleeman; Y. Sun; L. Sussel; J. Tong; M. O. Thorner; A. J. van der Lely

doi:10.1016/j.molmet.2015.03.005

Ghrelin

T. D. Müller, R. Nogueiras, M. L. Andermann, Z. B. Andrews, S. D. Anker, J. Argente, R. L. Batterham, S. C. Benoit, C. Y. Bowers, F. Broglio, F. F. Casanueva, D. D'Alessio, I. Depoortere, A. Geliebter, E. Ghigo, P. A. Cole, M. Cowley, D. E. Cummings, A. Dagher, S. DianoS. L. Dickson, C. Diéguez, R. Granata, H. J. Grill, K. Grove, K. M. Habegger, K. Heppner, M. L. Heiman, L. Holsen, B. Holst, A. Inui, J. O. Jansson, H. Kirchner, M. Korbonits, B. Laferrère, C. W. LeRoux, M. Lopez, S. Morin, M. Nakazato, R. Nass, D. Perez-Tilve, P. T. Pfluger, T. W. Schwartz, R. J. Seeley, M. Sleeman, Y. Sun, L. Sussel, J. Tong, M. O. Thorner, A. J. van der Lely

Medizinische Klinik I

293 Zitate (Scopus)

Abstract

The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the regulation of systemic energy metabolism. Scope of review: In this review, we discuss the diverse biological functions of ghrelin, the regulation of its secretion, and address questions that still remain 15 years after its discovery. Major conclusions: In recent years, ghrelin has been found to have a plethora of central and peripheral actions in distinct areas including learning and memory, gut motility and gastric acid secretion, sleep/wake rhythm, reward seeking behavior, taste sensation and glucose metabolism.

Originalsprache	Englisch
Zeitschrift	Molecular Metabolism
Jahrgang	4
Ausgabenummer	6
Seiten (von - bis)	437-460
Seitenumfang	24
ISSN	2212-8778
DOIs	https://doi.org/10.1016/j.molmet.2015.03.005
Publikationsstatus	Veröffentlicht - 01.01.2015

UN SDGs

Dieser Output leistet einen Beitrag zu folgendem(n) Ziel(en) für nachhaltige Entwicklung

Zugriff auf Dokument

10.1016/j.molmet.2015.03.005

Andere Dateien und Links

Link to publication in Scopus

Zitieren

Müller, T. D., Nogueiras, R., Andermann, M. L., Andrews, Z. B., Anker, S. D., Argente, J., Batterham, R. L., Benoit, S. C., Bowers, C. Y., Broglio, F., Casanueva, F. F., D'Alessio, D., Depoortere, I., Geliebter, A., Ghigo, E., Cole, P. A., Cowley, M., Cummings, D. E., Dagher, A., ... van der Lely, A. J. (2015). Ghrelin. Molecular Metabolism, 4(6), 437-460. https://doi.org/10.1016/j.molmet.2015.03.005

@article{cbcc64f6fcd745c6a1be0b8f3491de42,

title = "Ghrelin",

abstract = "The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the regulation of systemic energy metabolism. Scope of review: In this review, we discuss the diverse biological functions of ghrelin, the regulation of its secretion, and address questions that still remain 15 years after its discovery. Major conclusions: In recent years, ghrelin has been found to have a plethora of central and peripheral actions in distinct areas including learning and memory, gut motility and gastric acid secretion, sleep/wake rhythm, reward seeking behavior, taste sensation and glucose metabolism.",

author = "M{\"u}ller, {T. D.} and R. Nogueiras and Andermann, {M. L.} and Andrews, {Z. B.} and Anker, {S. D.} and J. Argente and Batterham, {R. L.} and Benoit, {S. C.} and Bowers, {C. Y.} and F. Broglio and Casanueva, {F. F.} and D. D'Alessio and I. Depoortere and A. Geliebter and E. Ghigo and Cole, {P. A.} and M. Cowley and Cummings, {D. E.} and A. Dagher and S. Diano and Dickson, {S. L.} and C. Di{\'e}guez and R. Granata and Grill, {H. J.} and K. Grove and Habegger, {K. M.} and K. Heppner and Heiman, {M. L.} and L. Holsen and B. Holst and A. Inui and Jansson, {J. O.} and H. Kirchner and M. Korbonits and B. Laferr{\`e}re and LeRoux, {C. W.} and M. Lopez and S. Morin and M. Nakazato and R. Nass and D. Perez-Tilve and Pfluger, {P. T.} and Schwartz, {T. W.} and Seeley, {R. J.} and M. Sleeman and Y. Sun and L. Sussel and J. Tong and Thorner, {M. O.} and {van der Lely}, {A. J.}",

year = "2015",

month = jan,

day = "1",

doi = "10.1016/j.molmet.2015.03.005",

language = "English",

volume = "4",

pages = "437--460",

journal = "Molecular Metabolism",

issn = "2212-8778",

number = "6",

}

Müller, TD, Nogueiras, R, Andermann, ML, Andrews, ZB, Anker, SD, Argente, J, Batterham, RL, Benoit, SC, Bowers, CY, Broglio, F, Casanueva, FF, D'Alessio, D, Depoortere, I, Geliebter, A, Ghigo, E, Cole, PA, Cowley, M, Cummings, DE, Dagher, A, Diano, S, Dickson, SL, Diéguez, C, Granata, R, Grill, HJ, Grove, K, Habegger, KM, Heppner, K, Heiman, ML, Holsen, L, Holst, B, Inui, A, Jansson, JO, Kirchner, H, Korbonits, M, Laferrère, B, LeRoux, CW, Lopez, M, Morin, S, Nakazato, M, Nass, R, Perez-Tilve, D, Pfluger, PT, Schwartz, TW, Seeley, RJ, Sleeman, M, Sun, Y, Sussel, L, Tong, J, Thorner, MO & van der Lely, AJ 2015, 'Ghrelin', Molecular Metabolism, Jg. 4, Nr. 6, S. 437-460. https://doi.org/10.1016/j.molmet.2015.03.005

TY - JOUR

T1 - Ghrelin

AU - Müller, T. D.

AU - Nogueiras, R.

AU - Andermann, M. L.

AU - Andrews, Z. B.

AU - Anker, S. D.

AU - Argente, J.

AU - Batterham, R. L.

AU - Benoit, S. C.

AU - Bowers, C. Y.

AU - Broglio, F.

AU - Casanueva, F. F.

AU - D'Alessio, D.

AU - Depoortere, I.

AU - Geliebter, A.

AU - Ghigo, E.

AU - Cole, P. A.

AU - Cowley, M.

AU - Cummings, D. E.

AU - Dagher, A.

AU - Diano, S.

AU - Dickson, S. L.

AU - Diéguez, C.

AU - Granata, R.

AU - Grill, H. J.

AU - Grove, K.

AU - Habegger, K. M.

AU - Heppner, K.

AU - Heiman, M. L.

AU - Holsen, L.

AU - Holst, B.

AU - Inui, A.

AU - Jansson, J. O.

AU - Kirchner, H.

AU - Korbonits, M.

AU - Laferrère, B.

AU - LeRoux, C. W.

AU - Lopez, M.

AU - Morin, S.

AU - Nakazato, M.

AU - Nass, R.

AU - Perez-Tilve, D.

AU - Pfluger, P. T.

AU - Schwartz, T. W.

AU - Seeley, R. J.

AU - Sleeman, M.

AU - Sun, Y.

AU - Sussel, L.

AU - Tong, J.

AU - Thorner, M. O.

AU - van der Lely, A. J.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the regulation of systemic energy metabolism. Scope of review: In this review, we discuss the diverse biological functions of ghrelin, the regulation of its secretion, and address questions that still remain 15 years after its discovery. Major conclusions: In recent years, ghrelin has been found to have a plethora of central and peripheral actions in distinct areas including learning and memory, gut motility and gastric acid secretion, sleep/wake rhythm, reward seeking behavior, taste sensation and glucose metabolism.

AB - The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the regulation of systemic energy metabolism. Scope of review: In this review, we discuss the diverse biological functions of ghrelin, the regulation of its secretion, and address questions that still remain 15 years after its discovery. Major conclusions: In recent years, ghrelin has been found to have a plethora of central and peripheral actions in distinct areas including learning and memory, gut motility and gastric acid secretion, sleep/wake rhythm, reward seeking behavior, taste sensation and glucose metabolism.

UR - http://www.scopus.com/inward/record.url?scp=84929964936&partnerID=8YFLogxK

U2 - 10.1016/j.molmet.2015.03.005

DO - 10.1016/j.molmet.2015.03.005

M3 - Scientific review articles

AN - SCOPUS:84929964936

SN - 2212-8778

VL - 4

SP - 437

EP - 460

JO - Molecular Metabolism

JF - Molecular Metabolism

IS - 6

ER -

Ghrelin

Abstract

UN SDGs

Zugriff auf Dokument

Andere Dateien und Links

Fingerprint

Zitieren