TY - JOUR
T1 - GERD und adjuvante Radiochemotherapie prädisponieren für rezidivierende Stimmprotheseninsuffizienz
AU - Jira, Daniel
AU - Pickhard, Anja
AU - Mair, Lena
AU - Zhu, Zhaojun
AU - Wollenberg, Barbara
AU - Buchberger, Anna Maria Stefanie
N1 - Publisher Copyright:
© 2020 Georg Thieme Verlag. All rights reserved.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/11/1
Y1 - 2020/11/1
N2 - After total laryngectomy, regaining ability to speech is a keystone in regards of life quality. Voice prostheses have been shown to be a sufficient tool for satisfying communication, although frequent replacements of prostheses are burdening certain patients. Therefore, a more accurate understanding of mechanisms of prosthetic leakage is urgently needed. Methods: We performed a retrospective analysis of 58 Patients after laryngectomy. Additionally, we analyzed pre-and post-therapeutic CT-scans of 22 Patients regarding pharyngeal stenosis. Results: In 40 Patients, at least one replacement of voice prosthesis was documented during observation period, median device life was 235 days. Patients treated with adjuvant radiotherapy (RT) showed a significantly longer device life than patients with adjuvant radio-chemotherapy (RCT, p = 0.002). Furthermore, patients suffering of gastroesophageal reflux disease (GERD) showed a significantly shortened device life (p = 0.04). 17 patients (42.5 %) suffered of clinically relevant stenosis of the neopharynx, which was treated with dilatation in 14 patients (82 %) and did not affect prosthesis device life. Conclusion: GERD is a risk factor for shortened voice prosthesis' device life and therefore should be treated effectively after laryngectomy. Also, adjuvant RCT predisposes a shortened device life. Stenosis is observed frequently after laryngectomy but does not affect device life when effectively treated.
AB - After total laryngectomy, regaining ability to speech is a keystone in regards of life quality. Voice prostheses have been shown to be a sufficient tool for satisfying communication, although frequent replacements of prostheses are burdening certain patients. Therefore, a more accurate understanding of mechanisms of prosthetic leakage is urgently needed. Methods: We performed a retrospective analysis of 58 Patients after laryngectomy. Additionally, we analyzed pre-and post-therapeutic CT-scans of 22 Patients regarding pharyngeal stenosis. Results: In 40 Patients, at least one replacement of voice prosthesis was documented during observation period, median device life was 235 days. Patients treated with adjuvant radiotherapy (RT) showed a significantly longer device life than patients with adjuvant radio-chemotherapy (RCT, p = 0.002). Furthermore, patients suffering of gastroesophageal reflux disease (GERD) showed a significantly shortened device life (p = 0.04). 17 patients (42.5 %) suffered of clinically relevant stenosis of the neopharynx, which was treated with dilatation in 14 patients (82 %) and did not affect prosthesis device life. Conclusion: GERD is a risk factor for shortened voice prosthesis' device life and therefore should be treated effectively after laryngectomy. Also, adjuvant RCT predisposes a shortened device life. Stenosis is observed frequently after laryngectomy but does not affect device life when effectively treated.
UR - http://www.scopus.com/inward/record.url?scp=85090974978&partnerID=8YFLogxK
U2 - 10.1055/a-1226-6927
DO - 10.1055/a-1226-6927
M3 - Zeitschriftenaufsätze
C2 - 32854119
AN - SCOPUS:85090974978
SN - 0935-8943
VL - 99
SP - 788
EP - 794
JO - Laryngo- Rhino- Otologie
JF - Laryngo- Rhino- Otologie
IS - 11
ER -