Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway

Houman Ashrafian^*, Gabor Czibik, Mohamed Bellahcene, Dunja Aksentijević, Anthony C. Smith, Sarah J. Mitchell, Michael S. Dodd, Jennifer Kirwan, Jonathan J. Byrne, Christian Ludwig, Henrik Isackson, Arash Yavari, Nicolaj B. Støttrup, Hussain Contractor, Thomas J. Cahill, Natasha Sahgal, Daniel R. Ball, Rune I.D. Birkler, Iain Hargreaves, Daniel A. TennantJohn Land, Craig A. Lygate, Mogens Johannsen, Rajesh K. Kharbanda, Stefan Neubauer, Charles Redwood, Rafael De Cabo, Ismayil Ahmet, Mark Talan, Ulrich L. Günther, Alan J. Robinson, Mark R. Viant, Patrick J. Pollard, Damian J. Tyler, Hugh Watkins

^*Korrespondierende/r Autor/-in für diese Arbeit

Institut für Chemie und Metabolomics

Oxford University Hospitals NHS Foundation Trust
Medical Research Council Mitochondrial Biology Unit
National Institute on Aging
University of Birmingham
Aarhus University
National Hospital of Neurology

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Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway

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Biochemistry, Genetics and Molecular Biology