Finite Element Simulation of Transcranial Current Stimulation in Realistic Rat Head Model

Fernando Gasca; Lisa Marshall; Sonja Binder; Alexander Schlaefer; Ulrich G. Hofmann; Achim Schweikard

doi:10.1109/NER.2011.5910483

Finite Element Simulation of Transcranial Current Stimulation in Realistic Rat Head Model

Fernando Gasca, Lisa Marshall, Sonja Binder, Alexander Schlaefer, Ulrich G. Hofmann, Achim Schweikard

Abstract

Transcranial current stimulation (tCS) is a method for modulating neural excitability and is used widely for studying brain function. Although tCS has been used on the rat, there is limited knowledge on the induced electric field distribution during stimulation. This work presents the finite element (FE) simulations of tCS in a realistic rat head model derived from MRI data. We simulated two electrode configurations and analyzed the spatial focality of the induced electric field for three implantation depth scenarios : (1) electrode implanted at the surface of the skull, (2) halfway through the skull and (3) in contact with cerebrospinal fluid. We quantitatively show the change in focality of stimulation with depth. This work emphasizes the importance of performing FE analysis in realistic models as a vital step in the design of tCS rat experiments. This can yield a better understanding of the location and intensity of stimulation, and its correlation to brain function.

Originalsprache	Englisch
Titel	2011 5th International IEEE/EMBS Conference on Neural Engineering
Seitenumfang	4
Herausgeber (Verlag)	IEEE
Erscheinungsdatum	20.07.2011
Seiten	36-39
Aufsatznummer	5910483
ISBN (Print)	978-1-4244-4140-2, 978-1-4244-4141-9
DOIs	https://doi.org/10.1109/NER.2011.5910483
Publikationsstatus	Veröffentlicht - 20.07.2011
Veranstaltung	2011 5th International IEEE/EMBS Conference on Neural Engineering - Cancun, Mexico Dauer: 27.04.2011 → 01.05.2011 Konferenznummer: 85524

UN SDGs

Dieser Output leistet einen Beitrag zu folgendem(n) Ziel(en) für nachhaltige Entwicklung

Dokumente

10.1109/NER.2011.5910483

Weitere Links

https://www.scopus.com/record/display.uri?eid=2-s2.0-79960341772&origin=inward&txGid=58cd8f6ad341d65ff7e61e7bf1aa77f8

Zitieren

Gasca, F., Marshall, L., Binder, S., Schlaefer, A., Hofmann, U. G., & Schweikard, A. (2011). Finite Element Simulation of Transcranial Current Stimulation in Realistic Rat Head Model. in 2011 5th International IEEE/EMBS Conference on Neural Engineering (S. 36-39). Artikel 5910483 (International IEEE/EMBS Conference on Neural Engineering). IEEE. https://doi.org/10.1109/NER.2011.5910483

@inproceedings{197355f5b13f4d048dc0c8fe2a747395,

title = "Finite Element Simulation of Transcranial Current Stimulation in Realistic Rat Head Model",

abstract = "Transcranial current stimulation (tCS) is a method for modulating neural excitability and is used widely for studying brain function. Although tCS has been used on the rat, there is limited knowledge on the induced electric field distribution during stimulation. This work presents the finite element (FE) simulations of tCS in a realistic rat head model derived from MRI data. We simulated two electrode configurations and analyzed the spatial focality of the induced electric field for three implantation depth scenarios : (1) electrode implanted at the surface of the skull, (2) halfway through the skull and (3) in contact with cerebrospinal fluid. We quantitatively show the change in focality of stimulation with depth. This work emphasizes the importance of performing FE analysis in realistic models as a vital step in the design of tCS rat experiments. This can yield a better understanding of the location and intensity of stimulation, and its correlation to brain function.",

author = "Fernando Gasca and Lisa Marshall and Sonja Binder and Alexander Schlaefer and Hofmann, {Ulrich G.} and Achim Schweikard",

year = "2011",

month = jul,

day = "20",

doi = "10.1109/NER.2011.5910483",

language = "English",

isbn = "978-1-4244-4140-2",

series = "International IEEE/EMBS Conference on Neural Engineering",

publisher = "IEEE",

pages = "36--39",

booktitle = "2011 5th International IEEE/EMBS Conference on Neural Engineering",

note = "2011 5th International IEEE/EMBS Conference on Neural Engineering , NER 2011 ; Conference date: 27-04-2011 Through 01-05-2011",

}

Gasca, F, Marshall, L , Binder, S, Schlaefer, A, Hofmann, UG & Schweikard, A 2011, Finite Element Simulation of Transcranial Current Stimulation in Realistic Rat Head Model. in 2011 5th International IEEE/EMBS Conference on Neural Engineering., 5910483, International IEEE/EMBS Conference on Neural Engineering, IEEE, S. 36-39, 2011 5th International IEEE/EMBS Conference on Neural Engineering , Cancun, Mexico, 27.04.11. https://doi.org/10.1109/NER.2011.5910483

Finite Element Simulation of Transcranial Current Stimulation in Realistic Rat Head Model. / Gasca, Fernando; Marshall, Lisa ; Binder, Sonja et al.
2011 5th International IEEE/EMBS Conference on Neural Engineering. IEEE, 2011. S. 36-39 5910483 (International IEEE/EMBS Conference on Neural Engineering).

Publikation: Kapitel in Büchern/Berichten/Konferenzbänden › Konferenzbeitrag › Begutachtung

TY - GEN

T1 - Finite Element Simulation of Transcranial Current Stimulation in Realistic Rat Head Model

AU - Gasca, Fernando

AU - Marshall, Lisa

AU - Binder, Sonja

AU - Schlaefer, Alexander

AU - Hofmann, Ulrich G.

AU - Schweikard, Achim

N1 - Conference code: 85524

PY - 2011/7/20

Y1 - 2011/7/20

N2 - Transcranial current stimulation (tCS) is a method for modulating neural excitability and is used widely for studying brain function. Although tCS has been used on the rat, there is limited knowledge on the induced electric field distribution during stimulation. This work presents the finite element (FE) simulations of tCS in a realistic rat head model derived from MRI data. We simulated two electrode configurations and analyzed the spatial focality of the induced electric field for three implantation depth scenarios : (1) electrode implanted at the surface of the skull, (2) halfway through the skull and (3) in contact with cerebrospinal fluid. We quantitatively show the change in focality of stimulation with depth. This work emphasizes the importance of performing FE analysis in realistic models as a vital step in the design of tCS rat experiments. This can yield a better understanding of the location and intensity of stimulation, and its correlation to brain function.

AB - Transcranial current stimulation (tCS) is a method for modulating neural excitability and is used widely for studying brain function. Although tCS has been used on the rat, there is limited knowledge on the induced electric field distribution during stimulation. This work presents the finite element (FE) simulations of tCS in a realistic rat head model derived from MRI data. We simulated two electrode configurations and analyzed the spatial focality of the induced electric field for three implantation depth scenarios : (1) electrode implanted at the surface of the skull, (2) halfway through the skull and (3) in contact with cerebrospinal fluid. We quantitatively show the change in focality of stimulation with depth. This work emphasizes the importance of performing FE analysis in realistic models as a vital step in the design of tCS rat experiments. This can yield a better understanding of the location and intensity of stimulation, and its correlation to brain function.

UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-79960341772&origin=inward&txGid=58cd8f6ad341d65ff7e61e7bf1aa77f8

U2 - 10.1109/NER.2011.5910483

DO - 10.1109/NER.2011.5910483

M3 - Conference contribution

SN - 978-1-4244-4140-2

SN - 978-1-4244-4141-9

T3 - International IEEE/EMBS Conference on Neural Engineering

SP - 36

EP - 39

BT - 2011 5th International IEEE/EMBS Conference on Neural Engineering

PB - IEEE

T2 - 2011 5th International IEEE/EMBS Conference on Neural Engineering

Y2 - 27 April 2011 through 1 May 2011

ER -

Finite Element Simulation of Transcranial Current Stimulation in Realistic Rat Head Model

Abstract

UN SDGs

Dokumente

Weitere Links

Fingerprint

Zitieren