Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin

H. P. Hauber; J. Galle; P. L. Chiodini; J. Rupp; R. Birke; E. Vollmer; P. Zabel; C. Lange

doi:10.1007/s15010-005-5060-x

Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin

H. P. Hauber, J. Galle, P. L. Chiodini, J. Rupp, R. Birke, E. Vollmer, P. Zabel, C. Lange^*

^*Korrespondierende/r Autor/-in für diese Arbeit

46 Zitate (Scopus)

Abstract

We report the case of a 77-year-oLd man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very low risk of Strongyloides transmission among healthcare workers.

Originalsprache	Englisch
Zeitschrift	Infection
Jahrgang	33
Ausgabenummer	5-6
Seiten (von - bis)	383-386
Seitenumfang	4
ISSN	0300-8126
DOIs	https://doi.org/10.1007/s15010-005-5060-x
Publikationsstatus	Veröffentlicht - 01.10.2005

UN SDGs

Dieser Output leistet einen Beitrag zu folgendem(n) Ziel(en) für nachhaltige Entwicklung

SDG 3 – Gesundheit und Wohlergehen

Strategische Forschungsbereiche und Zentren

Forschungsschwerpunkt: Infektion und Entzündung - Zentrum für Infektions- und Entzündungsforschung Lübeck (ZIEL)

Dokumente

10.1007/s15010-005-5060-x

Weitere Links

Link to publication in Scopus

Zitieren

@article{e7d6638d69ae447fab1002a57bbdfc5a,

title = "Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin",

abstract = "We report the case of a 77-year-oLd man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very low risk of Strongyloides transmission among healthcare workers.",

author = "Hauber, \{H. P.\} and J. Galle and Chiodini, \{P. L.\} and J. Rupp and R. Birke and E. Vollmer and P. Zabel and C. Lange",

year = "2005",

month = oct,

day = "1",

doi = "10.1007/s15010-005-5060-x",

language = "English",

volume = "33",

pages = "383--386",

journal = "Infection",

issn = "0300-8126",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "5-6",

}

TY - JOUR

T1 - Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin

AU - Hauber, H. P.

AU - Galle, J.

AU - Chiodini, P. L.

AU - Rupp, J.

AU - Birke, R.

AU - Vollmer, E.

AU - Zabel, P.

AU - Lange, C.

PY - 2005/10/1

Y1 - 2005/10/1

N2 - We report the case of a 77-year-oLd man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very low risk of Strongyloides transmission among healthcare workers.

AB - We report the case of a 77-year-oLd man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very low risk of Strongyloides transmission among healthcare workers.

UR - https://www.scopus.com/pages/publications/27644548042

U2 - 10.1007/s15010-005-5060-x

DO - 10.1007/s15010-005-5060-x

M3 - Journal articles

C2 - 16258873

AN - SCOPUS:27644548042

SN - 0300-8126

VL - 33

SP - 383

EP - 386

JO - Infection

JF - Infection

IS - 5-6

ER -

Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin

Abstract

UN SDGs

Strategische Forschungsbereiche und Zentren

Dokumente

Weitere Links

Fingerprint

Zitieren