Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin

H. P. Hauber; J. Galle; P. L. Chiodini; J. Rupp; R. Birke; E. Vollmer; P. Zabel; C. Lange

doi:10.1007/s15010-005-5060-x

Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin

H. P. Hauber, J. Galle, P. L. Chiodini, J. Rupp, R. Birke, E. Vollmer, P. Zabel, C. Lange^*

^*Korrespondierende/r Autor/-in für diese Arbeit

37 Zitate (Scopus)

Abstract

We report the case of a 77-year-oLd man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very low risk of Strongyloides transmission among healthcare workers.

Originalsprache	Englisch
Zeitschrift	Infection
Jahrgang	33
Ausgabenummer	5-6
Seiten (von - bis)	383-386
Seitenumfang	4
ISSN	0300-8126
DOIs	https://doi.org/10.1007/s15010-005-5060-x
Publikationsstatus	Veröffentlicht - 01.10.2005

Strategische Forschungsbereiche und Zentren

Forschungsschwerpunkt: Infektion und Entzündung - Zentrum für Infektions- und Entzündungsforschung Lübeck (ZIEL)

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abstract = "We report the case of a 77-year-oLd man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very low risk of Strongyloides transmission among healthcare workers.",

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AU - Hauber, H. P.

AU - Galle, J.

AU - Chiodini, P. L.

AU - Rupp, J.

AU - Birke, R.

AU - Vollmer, E.

AU - Zabel, P.

AU - Lange, C.

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N2 - We report the case of a 77-year-oLd man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very low risk of Strongyloides transmission among healthcare workers.

AB - We report the case of a 77-year-oLd man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very low risk of Strongyloides transmission among healthcare workers.

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ER -

Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin

Abstract

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