Faktenblatt: Epidemiologie der Tumoren des Endometriums in Deutschland

Background: Malignant tumors of the uterine corpus are the most common malignancies of the female genital tract in Germany, with endometrial cancer accounting for the majority of cases. This fact sheet provides an overview of the epidemiology of endometrial cancer in Germany. Methods: Data from the Centre for Cancer Registry Data (ZfKD) were analyzed for women diagnosed with endometrial cancer between 2006 and 2023. Age-standardized incidence and mortality rates, temporal trends assessed using joinpoint regression, and absolute and relative 3-, 5-, and 10-year survival probabilities were reported. Selected analyses were stratified by histological subtype, FIGO stage (International Federation of Gynecology and Obstetrics), and tumor grade. Results: Between 2019 and 2023, approximately 7000 cases of endometrial cancer were diagnosed annually in Germany. The majority of tumors were diagnosed at FIGO stage I (68,0%) and were low-grade (73,3%), although the distribution of FIGO stage and tumor grade changed significantly over the study period. The age-standardized incidence rate increased by 2,9% per year between 2006 and 2023. The 10-year relative survival was 80,8% overall and was highest among patients with FIGO stage I disease (93,5%). Conclusion: Despite the overall favorable prognosis, the increasing incidence and the shift toward more advanced stages and higher-grade tumors over time warrant further investigation.