TY - JOUR
T1 - Exploring the role of prolactin in psoriasis
AU - Langan, Ewan A.
AU - Griffiths, Christopher E.M.
AU - Paus, Ralf
PY - 2012/3/1
Y1 - 2012/3/1
N2 - Prolactin (PRL) is well recognised for its role(s) in mammary gland development and function. Moreover, its role in skin biology, including the potent regulation of human hair growth, is becoming clearer. Less widely appreciated, however, is the potential role of PRL in the pathobiology of psoriasis. While the relationship between PRL and psoriasis remains enigmatic, several recent publications on the PRL-psoriasis connection have demonstrated a reawakening of interest in this conundrum. We take the occasion of these reports to underscore the importance of dissecting the role(s) of PRL in the aetiopathology of psoriasis, not least since this may help to identify novel hormonal treatment strategies in its management.
AB - Prolactin (PRL) is well recognised for its role(s) in mammary gland development and function. Moreover, its role in skin biology, including the potent regulation of human hair growth, is becoming clearer. Less widely appreciated, however, is the potential role of PRL in the pathobiology of psoriasis. While the relationship between PRL and psoriasis remains enigmatic, several recent publications on the PRL-psoriasis connection have demonstrated a reawakening of interest in this conundrum. We take the occasion of these reports to underscore the importance of dissecting the role(s) of PRL in the aetiopathology of psoriasis, not least since this may help to identify novel hormonal treatment strategies in its management.
UR - http://www.scopus.com/inward/record.url?scp=84857898219&partnerID=8YFLogxK
U2 - 10.1007/s00403-012-1208-6
DO - 10.1007/s00403-012-1208-6
M3 - Short survey
C2 - 22249743
AN - SCOPUS:84857898219
SN - 0340-3696
VL - 304
SP - 115
EP - 118
JO - Archives of Dermatological Research
JF - Archives of Dermatological Research
IS - 2
ER -