Expanded motor and psychiatric phenotype in autosomal dominant Segawa syndrome due to GTP cyclohydrolase deficiency

Biochemistry, Genetics and Molecular Biology

• GTP Cyclohydrolase I 100%
• Autosomal Dominant Inheritance 100%
• Circadian Rhythm 20%
• Fibroblast 20%
• Population 20%
• Somnolence 20%
• Nightmare 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Syndrome 100%
• Dystonia 40%
• Autosomal Dominant Disorder 20%
• Obsessive Compulsive Disorder 20%
• Somnolence 20%
• Tendinitis 20%
• Nightmare 20%

Neuroscience

• Dystonia 40%
• Major Depressive Disorder 20%
• Sleep Disorder 20%
• Fibroblast 20%
• Serotonergic 20%
• Obsessive-Compulsive Disorder 20%
• Circadian Rhythm 20%
• Autosomal Dominant Disorder 20%
• Somnolence 20%
• Nightmare 20%