Exogenous levodopa is not toxic to elderly subjects with non-parkinsonian movement disorders: Further clinical evidence

J. Hagenah; C. Klein; M. Sieberer; P. Vieregge

doi:10.1007/s007020050159

Exogenous levodopa is not toxic to elderly subjects with non-parkinsonian movement disorders: Further clinical evidence

J. Hagenah, C. Klein, M. Sieberer, P. Vieregge^*

^*Korrespondierende/r Autor/-in für diese Arbeit

9 Zitate (Scopus)

Abstract

We report three women between 80 and 87 years of age who had longstanding essential tremor. Due to an erroneous diagnosis of Parkinsonism they had received levodopa preparations for 13, 16 and 25 years, respectively, with cumulative levodopa equivalent doses of 18.0, 9.0, and 4.1 kg. The patients showed neither dyskinesias nor signs of Parkinsonism. These observations do not support a detrimental role of chronic levodopa exposure in elderly individuals with essential tremor.

Originalsprache	Englisch
Zeitschrift	Journal of Neural Transmission
Jahrgang	106
Ausgabenummer	3-4
Seiten (von - bis)	301-307
Seitenumfang	7
ISSN	0300-9564
DOIs	https://doi.org/10.1007/s007020050159
Publikationsstatus	Veröffentlicht - 06.05.1999

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10.1007/s007020050159

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abstract = "We report three women between 80 and 87 years of age who had longstanding essential tremor. Due to an erroneous diagnosis of Parkinsonism they had received levodopa preparations for 13, 16 and 25 years, respectively, with cumulative levodopa equivalent doses of 18.0, 9.0, and 4.1 kg. The patients showed neither dyskinesias nor signs of Parkinsonism. These observations do not support a detrimental role of chronic levodopa exposure in elderly individuals with essential tremor.",

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AU - Vieregge, P.

PY - 1999/5/6

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N2 - We report three women between 80 and 87 years of age who had longstanding essential tremor. Due to an erroneous diagnosis of Parkinsonism they had received levodopa preparations for 13, 16 and 25 years, respectively, with cumulative levodopa equivalent doses of 18.0, 9.0, and 4.1 kg. The patients showed neither dyskinesias nor signs of Parkinsonism. These observations do not support a detrimental role of chronic levodopa exposure in elderly individuals with essential tremor.

AB - We report three women between 80 and 87 years of age who had longstanding essential tremor. Due to an erroneous diagnosis of Parkinsonism they had received levodopa preparations for 13, 16 and 25 years, respectively, with cumulative levodopa equivalent doses of 18.0, 9.0, and 4.1 kg. The patients showed neither dyskinesias nor signs of Parkinsonism. These observations do not support a detrimental role of chronic levodopa exposure in elderly individuals with essential tremor.

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Exogenous levodopa is not toxic to elderly subjects with non-parkinsonian movement disorders: Further clinical evidence

Abstract

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