Evaluation of local alterations in femoral bone mineral density measured via quantitative CT

A. Sitzer; L. Aulmann; R. Wendlandt; H. Handels; I. Weyers; A. P. Schulz; T. M. Buzug

doi:10.1515/cdbme-2015-0081

Evaluation of local alterations in femoral bone mineral density measured via quantitative CT

A. Sitzer
, L. Aulmann
, R. Wendlandt
, H. Handels
, I. Weyers
, A. P. Schulz
, T. M. Buzug

Abstract

Originalsprache	Englisch
Zeitschrift	Current Directions in Biomedical Engineering
Jahrgang	1
Ausgabenummer	1
Seiten (von - bis)	327-330
Seitenumfang	4
DOIs	https://doi.org/10.1515/cdbme-2015-0081
Publikationsstatus	Veröffentlicht - 12.09.2015

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10.1515/cdbme-2015-0081

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title = "Evaluation of local alterations in femoral bone mineral density measured via quantitative CT",

abstract = "The aim of this study was to investigate the accuracy of bone mineral density (BMD) determined by quantitative computed tomography (qCT) based on in situ and ex situ scans of cadavers of variable stature. The influence of surrounding tissue on the quantification of CT images of ex situ scanned femora was investigated in air and in water and compared with the in situ scanned femora. The study showed that the surrounding tissue has an impact on the grey value-based representation of the scanned object as well as on the calibration of BMD, influencing the determination of BMD. Local differences in BMD of up to 17.5\% were observed, which might originate from beam hardening artifacts.",

author = "A. Sitzer and L. Aulmann and R. Wendlandt and H. Handels and I. Weyers and Schulz, \{A. P.\} and Buzug, \{T. M.\}",

year = "2015",

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doi = "10.1515/cdbme-2015-0081",

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T1 - Evaluation of local alterations in femoral bone mineral density measured via quantitative CT

AU - Sitzer, A.

AU - Aulmann, L.

AU - Wendlandt, R.

AU - Handels, H.

AU - Weyers, I.

AU - Schulz, A. P.

AU - Buzug, T. M.

PY - 2015/9/12

Y1 - 2015/9/12

N2 - The aim of this study was to investigate the accuracy of bone mineral density (BMD) determined by quantitative computed tomography (qCT) based on in situ and ex situ scans of cadavers of variable stature. The influence of surrounding tissue on the quantification of CT images of ex situ scanned femora was investigated in air and in water and compared with the in situ scanned femora. The study showed that the surrounding tissue has an impact on the grey value-based representation of the scanned object as well as on the calibration of BMD, influencing the determination of BMD. Local differences in BMD of up to 17.5% were observed, which might originate from beam hardening artifacts.

AB - The aim of this study was to investigate the accuracy of bone mineral density (BMD) determined by quantitative computed tomography (qCT) based on in situ and ex situ scans of cadavers of variable stature. The influence of surrounding tissue on the quantification of CT images of ex situ scanned femora was investigated in air and in water and compared with the in situ scanned femora. The study showed that the surrounding tissue has an impact on the grey value-based representation of the scanned object as well as on the calibration of BMD, influencing the determination of BMD. Local differences in BMD of up to 17.5% were observed, which might originate from beam hardening artifacts.

U2 - 10.1515/cdbme-2015-0081

DO - 10.1515/cdbme-2015-0081

M3 - Journal articles

SN - 2364-5504

VL - 1

SP - 327

EP - 330

JO - Current Directions in Biomedical Engineering

JF - Current Directions in Biomedical Engineering

IS - 1

ER -

Evaluation of local alterations in femoral bone mineral density measured via quantitative CT

Abstract

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