Evaluation of a Mitochondrial Polygenic Score for Parkinson's Disease Across Ancestries

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: All authors report no conflicts of interest. A.H.T. serves as an associate editor for Elsevier, is employed by the University of Malaya, has received honoraria from the International Parkinson and Movement Disorder Society (MDS), Eisai, and Orion Pharma, and has received research funding from The Michael J. Fox Foundation for Parkinson's Research (MJFF) and the Global Parkinson's Genetic Program (GP2). K.A.B. serves on the scientific advisory board of G‐Can (the GBA1 Canadian Initiative) and has received honoraria from the same. K.A.B. is employed by Lund University and holds a subcontract with Queen Mary University of London (QMUL) for collaboration on the Aligning Science Across Parkinson's Global Parkinson's Genetics Program (ASAP‐GP2) and has received a grant from Parkinson's UK (G‐2403). A.C. has received grants from the German Research Foundation (DFG) (FOR2488, CA 1620/5‐1, CO 992/10‐2) and Kiel University (SEA‐EU Research Seed Fund 2024). K.M.A. was previously employed by the National Institutes of Health for the Center for Alzheimer's and Related Dementias and is currently a short‐term contractor with the Global Parkinson's Genetics Program (GP2) and The Michael J. Fox Foundation for Parkinson's Research (MJFF). L.J. is associated with a contract awarded to DataTecnica LLC by the National Institutes of Health. L.M.L. is employed by the Laboratories of Neurogenetics, National Institute on Aging, Bethesda, MD, USA, and has received a faculty honorarium from the MDS School Kuala Lumpur, Malaysia (July 2024). B.F. is a full‐time employee of The Michael J. Fox Foundation for Parkinson's Research (MJFF). C.K. serves as a consultant for Centogene, Takeda, Biogen, Bial, and the Lundbeck Foundation, is employed by the University of Lübeck and University Hospital Schleswig‐Holstein, has received speaker honoraria from Bial, royalties from Oxford University Press and Thieme Publishers, and grants from the German Research Foundation (DFG), The Michael J. Fox Foundation for Parkinson's Research (MJFF), and Aligning Science Across Parkinson's (ASAP). C.G., J.T., and T.L. are employed by the University of Lübeck and the University Hospital Schleswig‐Holstein, with J.T. also receiving grants from the German Research Foundation (DFG) Heisenberg and ZonMW MiGUT. Relevant Conflicts of Interest/Financial Disclosures This project was supported by the Global Parkinson's Genetics Program (GP2; https://gp2.org). GP2 is funded by the Aligning Science Across Parkinson’s (ASAP) initiative and implemented by The Michael J. Fox Foundation for Parkinson’s. For a complete list of GP2 members see https://gp2.org. This work was also supported in part by the Intramural Research Program of the National Institute on Aging, National Institutes of Health, Department of Health and Human Services (Project number ZO1 AG000535 and ZIA AG000949).