TY - CHAP
T1 - Embryo survival after vitrification of 2 PN oocytes
AU - Beyer, Daniel A.
AU - Amari, Feriel
AU - Diedrich, Klaus
AU - Hasani, Safaa Al
PY - 2011
Y1 - 2011
N2 - Objective: To assess embryo survival after vitrification of 2 PN oocytes and evaluate the impact of the duration of cold storage and patient age. Setting: Department of Obstetrics and Gynaecology, Division of Reproductive Endocrinology and Infertility, Schleswig-Holstein University, Campus Luebeck. Design: Retrospective study. Materials and methods: Cohort analysis of 576 thawing cycles after vitrification performed between 2004 and 2010. Results were used to construct a model to predict the embryo survival based on vitrification cycles. Data were categorized with respect to the duration of cold storage, number of 2 PN oocytes on each cryo-top, and patient age. Main outcome measures: The survival rate of 2 PN zygotes after thawing, implantation rate (IR) per transferred embryo, and clinical pregnancy rate (CPR). Results: In 576 thawed cycles, the survival rate of 1.349 2 PN warmed zygotes was 89.39%. Similar results concerning the survival rates of the 2 PN oocytes after thawing for all age groups (<30 years, 85.67%; 30-34 years, 89.21%; 35-40 years, 91.8%; >40 years, 99.9%) were noted. A total of 1159 embryos were transferred, leading to an overall IR of 7.72% and a CPR of 16.3%. The CPR decreased with age, as follows: CPR <30 years, 28.6%; 30-34 years, 16.5%; 35-40 years, 9.2%; >40 years, 5.8%. No significant association between the duration of cold storage and the number of 2 PN oocytes on each carrier on the embryo survival rate in question was observed. © 2010 Middle East Fertility Society.
AB - Objective: To assess embryo survival after vitrification of 2 PN oocytes and evaluate the impact of the duration of cold storage and patient age. Setting: Department of Obstetrics and Gynaecology, Division of Reproductive Endocrinology and Infertility, Schleswig-Holstein University, Campus Luebeck. Design: Retrospective study. Materials and methods: Cohort analysis of 576 thawing cycles after vitrification performed between 2004 and 2010. Results were used to construct a model to predict the embryo survival based on vitrification cycles. Data were categorized with respect to the duration of cold storage, number of 2 PN oocytes on each cryo-top, and patient age. Main outcome measures: The survival rate of 2 PN zygotes after thawing, implantation rate (IR) per transferred embryo, and clinical pregnancy rate (CPR). Results: In 576 thawed cycles, the survival rate of 1.349 2 PN warmed zygotes was 89.39%. Similar results concerning the survival rates of the 2 PN oocytes after thawing for all age groups (<30 years, 85.67%; 30-34 years, 89.21%; 35-40 years, 91.8%; >40 years, 99.9%) were noted. A total of 1159 embryos were transferred, leading to an overall IR of 7.72% and a CPR of 16.3%. The CPR decreased with age, as follows: CPR <30 years, 28.6%; 30-34 years, 16.5%; 35-40 years, 9.2%; >40 years, 5.8%. No significant association between the duration of cold storage and the number of 2 PN oocytes on each carrier on the embryo survival rate in question was observed. © 2010 Middle East Fertility Society.
U2 - 10.1016/j.mefs.2010.08.007
DO - 10.1016/j.mefs.2010.08.007
M3 - Chapter
SN - 1110-5690
T3 - Middle East Fertility Society Journal
SP - 45
EP - 49
BT - Middle East Fertility Society Journal
PB - Middle East Fertility Society
ER -
SDG 3 – Gesundheit und Wohlergehen