Effect of ultrasound on thrombolysis of middle cerebral artery occlusion

Jürgen Eggers; Björn Koch; Karsten Meyer; Inke König; Günter Scidel

doi:10.1002/ana.10590

Effect of ultrasound on thrombolysis of middle cerebral artery occlusion

Jürgen Eggers, Björn Koch, Karsten Meyer, Inke König, Günter Scidel^*

^*Korrespondierende/r Autor/-in für diese Arbeit

136 Zitate (Scopus)

Abstract

We studied the effect of transcranial 2MHz Doppler ultrasound (US) on the recanalization and outcome of stroke patients suffering from acute middle cerebral artery occlusion. All patients underwent intravenous recombinant tissue-type plasminogen activator thrombolysis. Eleven patients were randomly selected for continuous US monitoring (C-US) over 1 hour; 14 patients were selected for the control group. The C-US group showed a higher grade of recanalization after 1 hour but also a higher number of intraparenchymal bleedings. Overall, a favorable functional outcome occurred more frequently in the C-US group (Barthel index, p = 0.037) after 3 months.

Originalsprache	Englisch
Zeitschrift	Annals of Neurology
Jahrgang	53
Ausgabenummer	6
Seiten (von - bis)	797-800
Seitenumfang	4
ISSN	0364-5134
DOIs	https://doi.org/10.1002/ana.10590
Publikationsstatus	Veröffentlicht - 01.06.2003

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title = "Effect of ultrasound on thrombolysis of middle cerebral artery occlusion",

abstract = "We studied the effect of transcranial 2MHz Doppler ultrasound (US) on the recanalization and outcome of stroke patients suffering from acute middle cerebral artery occlusion. All patients underwent intravenous recombinant tissue-type plasminogen activator thrombolysis. Eleven patients were randomly selected for continuous US monitoring (C-US) over 1 hour; 14 patients were selected for the control group. The C-US group showed a higher grade of recanalization after 1 hour but also a higher number of intraparenchymal bleedings. Overall, a favorable functional outcome occurred more frequently in the C-US group (Barthel index, p = 0.037) after 3 months.",

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AU - Eggers, Jürgen

AU - Koch, Björn

AU - Meyer, Karsten

AU - König, Inke

AU - Scidel, Günter

PY - 2003/6/1

Y1 - 2003/6/1

N2 - We studied the effect of transcranial 2MHz Doppler ultrasound (US) on the recanalization and outcome of stroke patients suffering from acute middle cerebral artery occlusion. All patients underwent intravenous recombinant tissue-type plasminogen activator thrombolysis. Eleven patients were randomly selected for continuous US monitoring (C-US) over 1 hour; 14 patients were selected for the control group. The C-US group showed a higher grade of recanalization after 1 hour but also a higher number of intraparenchymal bleedings. Overall, a favorable functional outcome occurred more frequently in the C-US group (Barthel index, p = 0.037) after 3 months.

AB - We studied the effect of transcranial 2MHz Doppler ultrasound (US) on the recanalization and outcome of stroke patients suffering from acute middle cerebral artery occlusion. All patients underwent intravenous recombinant tissue-type plasminogen activator thrombolysis. Eleven patients were randomly selected for continuous US monitoring (C-US) over 1 hour; 14 patients were selected for the control group. The C-US group showed a higher grade of recanalization after 1 hour but also a higher number of intraparenchymal bleedings. Overall, a favorable functional outcome occurred more frequently in the C-US group (Barthel index, p = 0.037) after 3 months.

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DO - 10.1002/ana.10590

M3 - Journal articles

C2 - 12783427

AN - SCOPUS:0037766220

SN - 0364-5134

VL - 53

SP - 797

EP - 800

JO - Annals of Neurology

JF - Annals of Neurology

IS - 6

ER -

Effect of ultrasound on thrombolysis of middle cerebral artery occlusion

Abstract

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