Eastern cooperative oncology group performance score is associated with survival after radiotherapy of bone metastases from prostate cancer

Rapha Haus, Stefan Janssen, Steven E. Schild, Dirk Rades*

*Korrespondierende/r Autor/-in für diese Arbeit
2 Zitate (Scopus)

Abstract

Background/Aim: Understanding prognostic factors of survival are important for treatment personalization in cancer patients. This study aimed to identify such factors for patients irradiated for bone metastases from prostate cancer. Patients and Methods: Data from 74 patients irradiated between 01/2009 and 04/2019 were retrospectively evaluated. Ten characteristics were investigated for survival. Results: Median survival in the entire cohort was 12 months. Survival rates at 3, 6, 9 and 12 months were 84%, 73%, 56% and 47%, respectively. On univariate analyses, the Eastern Cooperative Oncology Group (ECOG) performance score of 0-1 was associated with improved survival (p<0.001), absence of visceral metastases (p=0.099) and only one irradiated metastatic site (p=0.099) showed a trend. On Cox regression analysis, only ECOG performance score (risk ratio=3.58, p<0.001) was significant. Conclusion: ECOG performance score is an independent prognostic factor of survival after irradiation of bone metastases from prostate cancer and may allow better personalization of care.

OriginalspracheEnglisch
ZeitschriftIn Vivo
Jahrgang34
Ausgabenummer2
Seiten (von - bis)679-682
Seitenumfang4
ISSN0258-851X
DOIs
PublikationsstatusVeröffentlicht - 2020

Fingerprint

Untersuchen Sie die Forschungsthemen von „Eastern cooperative oncology group performance score is associated with survival after radiotherapy of bone metastases from prostate cancer“. Zusammen bilden sie einen einzigartigen Fingerprint.

Zitieren