Down syndrome and male fertility: PCR‐derived fingerprinting, serological and andrological investigations

Christine Zühlke; Ulrike Thies; Ingrid Braulke; André Reis; Carl Schirren

doi:10.1111/j.1399-0004.1994.tb04171.x

Down syndrome and male fertility: PCR‐derived fingerprinting, serological and andrological investigations

Christine Zühlke^*, Ulrike Thies, Ingrid Braulke, André Reis, Carl Schirren

^*Korrespondierende/r Autor/-in für diese Arbeit

Institut für Humangenetik

30 Zitate (Scopus)

Abstract

Down syndrome, the most common birth defect causing mental retardation, is characterized by a specific phenotype including subfertility or sterility and hypogonadism in males. In contrast, several females with Down syndrome have borne offspring. Here, a male with trisomy 21 fathering an infant is described. This observation is verified by serological markers, DNA fingerprinting using different DNA micro‐or minisatellites and andrological investigations.

Originalsprache	Englisch
Zeitschrift	Clinical Genetics
Jahrgang	46
Ausgabenummer	4
Seiten (von - bis)	324-326
Seitenumfang	3
ISSN	0009-9163
DOIs	https://doi.org/10.1111/j.1399-0004.1994.tb04171.x
Publikationsstatus	Veröffentlicht - 10.1994

Strategische Forschungsbereiche und Zentren

Querschnittsbereich: Medizinische Genetik

UN SDGs

Dieser Output leistet einen Beitrag zu folgendem(n) Ziel(en) für nachhaltige Entwicklung

Dokumente

10.1111/j.1399-0004.1994.tb04171.x

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AU - Zühlke, Christine

AU - Thies, Ulrike

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AU - Reis, André

AU - Schirren, Carl

PY - 1994/10

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AB - Down syndrome, the most common birth defect causing mental retardation, is characterized by a specific phenotype including subfertility or sterility and hypogonadism in males. In contrast, several females with Down syndrome have borne offspring. Here, a male with trisomy 21 fathering an infant is described. This observation is verified by serological markers, DNA fingerprinting using different DNA micro‐or minisatellites and andrological investigations.

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Down syndrome and male fertility: PCR‐derived fingerprinting, serological and andrological investigations

Abstract

Strategische Forschungsbereiche und Zentren

UN SDGs

Dokumente

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