Distinct Impact of Phosphodiesterade-4 (PDE4) Inhibition in Two Pre-clinical Psoriasis Models

Fördermittel

The authors would like to thank Ibrahim Osman Ibrahim and Saeedeh Ghorbanalipoorfor assisting with the mouse experiments. ChatGPT 4o was used to enhance readability and language. Funding sources: This research was funded by the Cluster of Excellence “Precision Medicine in Chronic Inflammation” (EXC 2167) and the Research Training Group “Modulation of Autoimmunity” (GRK 1727), both from the Deutsche Forschungsgemeinschaft, the Schleswig-Holstein Excellence-Chair Program from the State of Schleswig Holstein, and an unrestricted research grant from Topadur Pharma. IRB approval status: Animal experimentation was approved by the respective governmental administration (AZ 92-7/17). Conflict of interest disclosures: RJL received funding from Topa-dur Pharma AG to investigate the impact of PDE4 inhibition in preclinical models of inflammatory skin diseases. HT is a full-time employee at TOPADUR Pharma AG.