Differentially expressed genes of reprogrammed human pluripotent stem cells in breast cancer

A. Rody; T. Karn; E. Ruckhaeberle; L. Hanker; R. Gaetje; U. Holtrich; M. Kaufmann

doi:10.1016/j.ejca.2008.06.037

Differentially expressed genes of reprogrammed human pluripotent stem cells in breast cancer

A. Rody^*, T. Karn, E. Ruckhaeberle, L. Hanker, R. Gaetje, U. Holtrich, M. Kaufmann

^*Korrespondierende/r Autor/-in für diese Arbeit

Klinik für Frauenheilkunde und Geburtshilfe

Johann Wolfgang Goethe-Universität

8 Zitate (Scopus)

Abstract

Reprogramming of human somatic cells into pluripotent cell types gives insight in the pathophysiology of diseases. We analysed genes recently shown to be differentially expressed in induced pluripotent stem cells (iPS) in 95 breast cancer samples. This analysis reveals two breast cancer subgroups with stem cell-like features, differing in ER-status and proliferation as well as in their clinical course of disease.

Originalsprache	Englisch
Zeitschrift	European Journal of Cancer
Jahrgang	44
Ausgabenummer	13
Seiten (von - bis)	1789-1792
Seitenumfang	4
ISSN	0959-8049
DOIs	https://doi.org/10.1016/j.ejca.2008.06.037
Publikationsstatus	Veröffentlicht - 09.2008

Fördermittel

We thank Samira Adel and Katherina Kourtis for expert technical assistance. This work was supported by grants from the Deutsche Krebshilfe, Bonn, the Margarete Bonifer-Stiftung, Bad Soden, the BANSS-Stiftung, Biedenkopf and the Dr. Robert Pfleger-Stiftung, Bamberg.

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10.1016/j.ejca.2008.06.037

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title = "Differentially expressed genes of reprogrammed human pluripotent stem cells in breast cancer",

abstract = "Reprogramming of human somatic cells into pluripotent cell types gives insight in the pathophysiology of diseases. We analysed genes recently shown to be differentially expressed in induced pluripotent stem cells (iPS) in 95 breast cancer samples. This analysis reveals two breast cancer subgroups with stem cell-like features, differing in ER-status and proliferation as well as in their clinical course of disease.",

author = "A. Rody and T. Karn and E. Ruckhaeberle and L. Hanker and R. Gaetje and U. Holtrich and M. Kaufmann",

note = "Funding Information: We thank Samira Adel and Katherina Kourtis for expert technical assistance. This work was supported by grants from the Deutsche Krebshilfe, Bonn, the Margarete Bonifer-Stiftung, Bad Soden, the BANSS-Stiftung, Biedenkopf and the Dr. Robert Pfleger-Stiftung, Bamberg.",

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doi = "10.1016/j.ejca.2008.06.037",

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T1 - Differentially expressed genes of reprogrammed human pluripotent stem cells in breast cancer

AU - Rody, A.

AU - Karn, T.

AU - Ruckhaeberle, E.

AU - Hanker, L.

AU - Gaetje, R.

AU - Holtrich, U.

AU - Kaufmann, M.

N1 - Funding Information: We thank Samira Adel and Katherina Kourtis for expert technical assistance. This work was supported by grants from the Deutsche Krebshilfe, Bonn, the Margarete Bonifer-Stiftung, Bad Soden, the BANSS-Stiftung, Biedenkopf and the Dr. Robert Pfleger-Stiftung, Bamberg.

PY - 2008/9

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N2 - Reprogramming of human somatic cells into pluripotent cell types gives insight in the pathophysiology of diseases. We analysed genes recently shown to be differentially expressed in induced pluripotent stem cells (iPS) in 95 breast cancer samples. This analysis reveals two breast cancer subgroups with stem cell-like features, differing in ER-status and proliferation as well as in their clinical course of disease.

AB - Reprogramming of human somatic cells into pluripotent cell types gives insight in the pathophysiology of diseases. We analysed genes recently shown to be differentially expressed in induced pluripotent stem cells (iPS) in 95 breast cancer samples. This analysis reveals two breast cancer subgroups with stem cell-like features, differing in ER-status and proliferation as well as in their clinical course of disease.

UR - https://www.scopus.com/pages/publications/49549087078

U2 - 10.1016/j.ejca.2008.06.037

DO - 10.1016/j.ejca.2008.06.037

M3 - Journal articles

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AN - SCOPUS:49549087078

SN - 0959-8049

VL - 44

SP - 1789

EP - 1792

JO - European Journal of Cancer

JF - European Journal of Cancer

IS - 13

ER -

Differentially expressed genes of reprogrammed human pluripotent stem cells in breast cancer

Abstract

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