TY - JOUR
T1 - Differentially expressed genes of reprogrammed human pluripotent stem cells in breast cancer
AU - Rody, A.
AU - Karn, T.
AU - Ruckhaeberle, E.
AU - Hanker, L.
AU - Gaetje, R.
AU - Holtrich, U.
AU - Kaufmann, M.
N1 - Funding Information:
We thank Samira Adel and Katherina Kourtis for expert technical assistance. This work was supported by grants from the Deutsche Krebshilfe, Bonn, the Margarete Bonifer-Stiftung, Bad Soden, the BANSS-Stiftung, Biedenkopf and the Dr. Robert Pfleger-Stiftung, Bamberg.
PY - 2008/9
Y1 - 2008/9
N2 - Reprogramming of human somatic cells into pluripotent cell types gives insight in the pathophysiology of diseases. We analysed genes recently shown to be differentially expressed in induced pluripotent stem cells (iPS) in 95 breast cancer samples. This analysis reveals two breast cancer subgroups with stem cell-like features, differing in ER-status and proliferation as well as in their clinical course of disease.
AB - Reprogramming of human somatic cells into pluripotent cell types gives insight in the pathophysiology of diseases. We analysed genes recently shown to be differentially expressed in induced pluripotent stem cells (iPS) in 95 breast cancer samples. This analysis reveals two breast cancer subgroups with stem cell-like features, differing in ER-status and proliferation as well as in their clinical course of disease.
UR - http://www.scopus.com/inward/record.url?scp=49549087078&partnerID=8YFLogxK
U2 - 10.1016/j.ejca.2008.06.037
DO - 10.1016/j.ejca.2008.06.037
M3 - Journal articles
C2 - 18691884
AN - SCOPUS:49549087078
SN - 0959-8049
VL - 44
SP - 1789
EP - 1792
JO - European Journal of Cancer
JF - European Journal of Cancer
IS - 13
ER -
