Depressive symptoms in Parkinson’s disease are insufficiently but more often treated than in other chronic conditions

EPIPARK Study Group

Abstract

Depressive symptoms in Parkinson’s disease (PD) are multifactorial and are partly linked to the underlying dopaminergic deficit. However, at least a subset of PD patients may exhibit an unspecific depressive reaction to chronic illness. Here, we compared the prevalence and severity of depressive symptoms in PD patients and disease controls (DC). PD patients reported depressive symptoms at similar frequencies as DC but were on antidepressants, especially Mirtazapine, more frequently. Still, in both groups, a high proportion of patients with clinically significant depressive symptoms was not receiving medication. Diagnosis and treatment of depressive symptoms both in PD and DC should be improved.

OriginalspracheEnglisch
Aufsatznummer113
ZeitschriftNPJ Parkinson's disease
Jahrgang9
Ausgabenummer1
ISSN2373-8057
DOIs
PublikationsstatusVeröffentlicht - 12.2023

Strategische Forschungsbereiche und Zentren

  • Forschungsschwerpunkt: Gehirn, Hormone, Verhalten - Center for Brain, Behavior and Metabolism (CBBM)

DFG-Fachsystematik

  • 206-07 Klinische Neurologie; Neurochirurgie und Neuroradiologie
  • 206-08 Kognitive und Systemische Humanneurowissenschaften
  • 206-10 Klinische Psychiatrie, Psychotherapie und Kinder- und Jugendpsychiatrie

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