TY - JOUR
T1 - Construction of a Spectrometer to Measure the Cotton-Mouton Effect of Superparamagnetic Iron Oxide Nanoparticles
AU - Krieger, J.
AU - Köhler, K.
AU - Graeser, M.
AU - Lüdtke-Buzug, K.
PY - 2013/9/7
Y1 - 2013/9/7
N2 - Superparamagnetic iron oxide nanoparticles (SPIONs) are biocompatible and their outstanding properties make them the most used magnetic nanoparticles in biomedicine [1]. SPIONs, for instance, are used as tracer material for the new imaging modality Magnetic Particle Imaging (MPI). In this application, the particle size is of crucial importance for imaging quality. In this project, the development, the construction and implementation of a new spectrometer to measure the size of SPIONs is described. The spectrometer is based on the Cotton Mouton Effect (CME). As part of this work, the experimental setup has been established and analysis software has been implemented. First measurements with SPIONs of a hydrodynamic diameter of 100 nm have demonstrated the potential of this technique.
AB - Superparamagnetic iron oxide nanoparticles (SPIONs) are biocompatible and their outstanding properties make them the most used magnetic nanoparticles in biomedicine [1]. SPIONs, for instance, are used as tracer material for the new imaging modality Magnetic Particle Imaging (MPI). In this application, the particle size is of crucial importance for imaging quality. In this project, the development, the construction and implementation of a new spectrometer to measure the size of SPIONs is described. The spectrometer is based on the Cotton Mouton Effect (CME). As part of this work, the experimental setup has been established and analysis software has been implemented. First measurements with SPIONs of a hydrodynamic diameter of 100 nm have demonstrated the potential of this technique.
U2 - 10.1515/bmt-2013-4102
DO - 10.1515/bmt-2013-4102
M3 - Journal articles
SN - 0013-5585
VL - 58
SP - 1
EP - 2
JO - Biomedizinische Technik
JF - Biomedizinische Technik
ER -