COMPLEMENT-FRAGMENT C3d IM PLASMA VON PATIENTEN MIT CHRONISCHER POLYARTHRITIS

S. Stannat; H. H. Peter; H. H. Raspe; H. Deicher

COMPLEMENT-FRAGMENT C3d IM PLASMA VON PATIENTEN MIT CHRONISCHER POLYARTHRITIS

S. Stannat, H. H. Peter, H. H. Raspe, H. Deicher

Institut für Sozialmedizin und Epidemiologie

Medizinische Hochschule Hannover

1 Zitat (Scopus)

Abstract

Activation of the complement system via immune complex formation plays an important role in the perpetuation of chronic inflammatory disorders. The serum levels of C3 or C4 do not necessarily reflect the actual complement catabolism. By measurement of the long-lived C3 split product 'C3d' direct information about complement activation can be obtained. C3d was measured with a modified immunoelectrophoresis technique in EDTA-plasma of 106 patients with rheumatoid arthritis. 36% of them showed significantly elevated C3d levels (mean: 8.93 μg/ml). Significant linear correlations were found for C3d with ESR, Lansbury index and plasma viscosity.

Titel in Übersetzung	Complement fragment C3d in plasma from patients with chronic rheumatoid arthritis
Originalsprache	Deutsch
Zeitschrift	Zeitschrift fur Rheumatologie
Jahrgang	45
Ausgabenummer	2
Seiten (von - bis)	47-51
Seitenumfang	5
ISSN	0340-1855
Publikationsstatus	Veröffentlicht - 1986

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title = "COMPLEMENT-FRAGMENT C3d IM PLASMA VON PATIENTEN MIT CHRONISCHER POLYARTHRITIS",

abstract = "Activation of the complement system via immune complex formation plays an important role in the perpetuation of chronic inflammatory disorders. The serum levels of C3 or C4 do not necessarily reflect the actual complement catabolism. By measurement of the long-lived C3 split product 'C3d' direct information about complement activation can be obtained. C3d was measured with a modified immunoelectrophoresis technique in EDTA-plasma of 106 patients with rheumatoid arthritis. 36\% of them showed significantly elevated C3d levels (mean: 8.93 μg/ml). Significant linear correlations were found for C3d with ESR, Lansbury index and plasma viscosity.",

author = "S. Stannat and Peter, \{H. H.\} and Raspe, \{H. H.\} and H. Deicher",

year = "1986",

language = "Deutsch",

volume = "45",

pages = "47--51",

journal = "Zeitschrift fur Rheumatologie",

issn = "0340-1855",

publisher = "Springer Medizin",

number = "2",

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TY - JOUR

T1 - COMPLEMENT-FRAGMENT C3d IM PLASMA VON PATIENTEN MIT CHRONISCHER POLYARTHRITIS

AU - Stannat, S.

AU - Peter, H. H.

AU - Raspe, H. H.

AU - Deicher, H.

PY - 1986

Y1 - 1986

N2 - Activation of the complement system via immune complex formation plays an important role in the perpetuation of chronic inflammatory disorders. The serum levels of C3 or C4 do not necessarily reflect the actual complement catabolism. By measurement of the long-lived C3 split product 'C3d' direct information about complement activation can be obtained. C3d was measured with a modified immunoelectrophoresis technique in EDTA-plasma of 106 patients with rheumatoid arthritis. 36% of them showed significantly elevated C3d levels (mean: 8.93 μg/ml). Significant linear correlations were found for C3d with ESR, Lansbury index and plasma viscosity.

AB - Activation of the complement system via immune complex formation plays an important role in the perpetuation of chronic inflammatory disorders. The serum levels of C3 or C4 do not necessarily reflect the actual complement catabolism. By measurement of the long-lived C3 split product 'C3d' direct information about complement activation can be obtained. C3d was measured with a modified immunoelectrophoresis technique in EDTA-plasma of 106 patients with rheumatoid arthritis. 36% of them showed significantly elevated C3d levels (mean: 8.93 μg/ml). Significant linear correlations were found for C3d with ESR, Lansbury index and plasma viscosity.

UR - https://www.scopus.com/pages/publications/0022557035

M3 - Zeitschriftenaufsätze

C2 - 3487899

AN - SCOPUS:0022557035

SN - 0340-1855

VL - 45

SP - 47

EP - 51

JO - Zeitschrift fur Rheumatologie

JF - Zeitschrift fur Rheumatologie

IS - 2

ER -

COMPLEMENT-FRAGMENT C3d IM PLASMA VON PATIENTEN MIT CHRONISCHER POLYARTHRITIS

Abstract

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