Abstract
Background: In 2002, colonoscopy was introduced as a tool for colorectal cancer screening in Germany. The long-term objective was to reduce the incidence in colorectal cancer (CRC) by detection and removal of advanced adenomas. Currently, the effect of colonoscopy screening on the population-based incidence of CRC in Germany is unknown. Methods: We provide data on stage-specific (age-standardized) incidence rates in three federal states in Germany, 6 years after the implementation of colonoscopy. Results: Between 2002 and 2008 a statistically significant decrease in CRC incidence could be observed (annually 3.0%, 95% confidence interval [CI]: -3.8; -2.2). The decline could be observed in all advanced tumor categories (T2, T3, and T4), whereas the incidence of in situ carcinomas (Tis) increased annually by 51.6% (95% CI: 28.0; 79.4) until 2004, and remained stable until 2008. Conclusion: The observed changes cannot be attributed definitively to the screening activities, but the presented data support a possible causal association.
Originalsprache | Englisch |
---|---|
Zeitschrift | Cancer Epidemiology |
Jahrgang | 36 |
Ausgabenummer | 5 |
Seiten (von - bis) | 417-420 |
Seitenumfang | 4 |
ISSN | 1877-7821 |
DOIs | |
Publikationsstatus | Veröffentlicht - 01.10.2012 |
Strategische Forschungsbereiche und Zentren
- Profilbereich: Zentrum für Bevölkerungsmedizin und Versorgungsforschung (ZBV)
DFG-Fachsystematik
- 2.22-02 Public Health, gesundheitsbezogene Versorgungsforschung, Sozial- und Arbeitsmedizin
- 2.22-14 Hämatologie, Onkologie
- 2.22-25 Allgemein- und Viszeralchirurgie