Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican

Courtney C. Hong, Alan T. Tang, Matthew R. Detter, Jaesung P. Choi, Rui Wang, Xi Yang, Andrea A. Guerrero, Carl F. Wittig, Nicholas Hobson, Romuald Girard, Rhonda Lightle, Thomas Moore, Robert Shenkar, Sean P. Polster, Lauren M. Goddard, Aileen A. Ren, N. Adrian Leu, Stephanie Sterling, Jisheng Yang, Li LiMei Chen, Patricia Mericko-Ishizuka, Lukas E. Dow, Hideto Watanabe, Markus Schwaninger, Wang Min, Douglas A. Marchuk, Xiangjian Zheng, Issam A. Awad, Mark L. Kahn^*

^*Korrespondierende/r Autor/-in für diese Arbeit

Institut für Experimentelle und Klinische Pharmakologie und Toxikologie

University of Pennsylvania
Duke University
Tianjian Medical University
University of Chicago
Weill Cornell Medical College
Aichi Medical University
Yale University

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Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican

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Biochemistry, Genetics and Molecular Biology