Cerebellar activation in opsoclonus: An fMRI study

Christoph Helmchen; H. Rambold; A. Sprenger; C. Erdmann; F. Binkofski

doi:10.1212/01.WNL.0000073271.66866.51

Cerebellar activation in opsoclonus: An fMRI study

Christoph Helmchen^*, H. Rambold, A. Sprenger, C. Erdmann, F. Binkofski

^*Korrespondierende/r Autor/-in für diese Arbeit

Klinik für Neurologie

75 Zitate (Scopus)

Abstract

It is controversial whether opsoclonus is a cerebellar or brainstem disorder. Two patients whose opsoclonus largely disappeared on eye closure underwent fMRI FMRI. A comparison of these two states revealed neither vermal nor brainstem activation but rather a bilateral activation in the deep cerebellar nuclei in excess of what the authors found in healthy subjects. The results support a crucial role of the fastigial nucleus in opsoclonus.

Originalsprache	Englisch
Zeitschrift	Neurology
Jahrgang	61
Ausgabenummer	3
Seiten (von - bis)	412-415
Seitenumfang	4
ISSN	0028-3878
DOIs	https://doi.org/10.1212/01.WNL.0000073271.66866.51
Publikationsstatus	Veröffentlicht - 12.08.2003

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Forschungsschwerpunkt: Gehirn, Hormone, Verhalten - Center for Brain, Behavior and Metabolism (CBBM)

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10.1212/01.WNL.0000073271.66866.51

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AU - Binkofski, F.

PY - 2003/8/12

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AB - It is controversial whether opsoclonus is a cerebellar or brainstem disorder. Two patients whose opsoclonus largely disappeared on eye closure underwent fMRI FMRI. A comparison of these two states revealed neither vermal nor brainstem activation but rather a bilateral activation in the deep cerebellar nuclei in excess of what the authors found in healthy subjects. The results support a crucial role of the fastigial nucleus in opsoclonus.

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Cerebellar activation in opsoclonus: An fMRI study

Abstract

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