Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion [6]

Christoph Helmchen; Stefan Gottschalk; Thurid Sander; Peter Trillenberg; Holger Rambold; Andreas Sprenger

doi:10.1007/s00415-006-0448-9

Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion [6]

Christoph Helmchen^*, Stefan Gottschalk, Thurid Sander, Peter Trillenberg, Holger Rambold, Andreas Sprenger

^*Korrespondierende/r Autor/-in für diese Arbeit

17 Zitate (Scopus)

Abstract

Sirs: Central positioning downbeat nystagmus (pDBN) presents with transient nystagmus in supine or the head hanging position in the absence of DBN in the head erect position. In contrast to central positional downbeat nystagmus, pDBN requires rapid head posi- tioning manoeuvres to be elicited. The pathomechanism and therapy of central pDBN is not yet known and circumscribed lesions are missing so far [1, 2]. We examined the effect of 3,4-diaminopyridine (DAP) [3, 4] on the oculomotor behavior of a patient with pDBN.

Originalsprache	Englisch
Zeitschrift	Journal of Neurology
Jahrgang	254
Ausgabenummer	8
Seiten (von - bis)	1126-1128
Seitenumfang	3
ISSN	0340-5354
DOIs	https://doi.org/10.1007/s00415-006-0448-9
Publikationsstatus	Veröffentlicht - 01.08.2007

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Forschungsschwerpunkt: Gehirn, Hormone, Verhalten - Center for Brain, Behavior and Metabolism (CBBM)

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abstract = "Sirs: Central positioning downbeat nystagmus (pDBN) presents with transient nystagmus in supine or the head hanging position in the absence of DBN in the head erect position. In contrast to central positional downbeat nystagmus, pDBN requires rapid head posi- tioning manoeuvres to be elicited. The pathomechanism and therapy of central pDBN is not yet known and circumscribed lesions are missing so far [1, 2]. We examined the effect of 3,4-diaminopyridine (DAP) [3, 4] on the oculomotor behavior of a patient with pDBN.",

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AU - Helmchen, Christoph

AU - Gottschalk, Stefan

AU - Sander, Thurid

AU - Trillenberg, Peter

AU - Rambold, Holger

AU - Sprenger, Andreas

PY - 2007/8/1

Y1 - 2007/8/1

N2 - Sirs: Central positioning downbeat nystagmus (pDBN) presents with transient nystagmus in supine or the head hanging position in the absence of DBN in the head erect position. In contrast to central positional downbeat nystagmus, pDBN requires rapid head posi- tioning manoeuvres to be elicited. The pathomechanism and therapy of central pDBN is not yet known and circumscribed lesions are missing so far [1, 2]. We examined the effect of 3,4-diaminopyridine (DAP) [3, 4] on the oculomotor behavior of a patient with pDBN.

AB - Sirs: Central positioning downbeat nystagmus (pDBN) presents with transient nystagmus in supine or the head hanging position in the absence of DBN in the head erect position. In contrast to central positional downbeat nystagmus, pDBN requires rapid head posi- tioning manoeuvres to be elicited. The pathomechanism and therapy of central pDBN is not yet known and circumscribed lesions are missing so far [1, 2]. We examined the effect of 3,4-diaminopyridine (DAP) [3, 4] on the oculomotor behavior of a patient with pDBN.

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Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion [6]

Abstract

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