Behavioral outcome measures to improve experimental stroke research

Mustafa G. Balkaya, Rebecca C. Trueman, Johannes Boltze, Dale Corbett, Jukka Jolkkonen*

*Korrespondierende/r Autor/-in für diese Arbeit
4 Zitate (Scopus)

Abstract

Functional recovery after an experimental stroke can be assessed by multiple behavioral tests, however, there is no consensus about which test to use in long-term stroke recovery studies or whether the tests are affected by stroke surgery, post-operative care or behavioral compensation due to repeated testing. This review describes the tests most commonly used to assess motor and sensorimotor function, cognition and mood in stroke animals. Although it is difficult to predict the direction of future research, it may be possible to prevent false-positive results by selecting an appropriate task or a battery of tasks. It is also expected that the upcoming stroke recovery recommendations and the improved dialogue between academy, industry and healthcare professionals will further promote translational success.

OriginalspracheEnglisch
ZeitschriftBehavioural Brain Research
Jahrgang352
Seiten (von - bis)161-171
Seitenumfang11
ISSN0166-4328
DOIs
PublikationsstatusVeröffentlicht - 15.10.2018

Strategische Forschungsbereiche und Zentren

  • Forschungsschwerpunkt: Biomedizintechnik

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