Bedeutende organbezogene langzeitfolgen von chemotherapie und sekundärmalignome

With rising survival rates after treatment for childhood and adolescence cancer, long-term effects of cancer treatment are becoming more important, especially since these can heavily affect the quality of life of the former cancer patients or even become life-threatening. The aftercare of these patients is of particular importance also under these aspects. Severe long-term sequelae can manifest in practically every organ system, depending on the treatment received. The most adverse events are secondary malignancies or anthracycline-induced cardiomyopathy. The detection of these organ impairments via simple, but sensitive, methods is feasible, so that the aftercare can be performed by a general practitioner near the place of residence. Of notable value are national vertical networks (Late Effects Surveillance System), which give recommendations for follow-up and fulfill advisory roles, so that an integrated aftercare becomes possible for the patients.