Association of the CD226 Ser307 variant with systemic sclerosis

P. Dieudé; M. Guedj; M. E. Truchetet; J. Wipff; L. Revillod; G. Riemekasten; M. Matucci-Cerinic; I. Melchers; E. Hachulla; P. Airo; E. Diot; N. Hunzelmann; L. Mouthon; J. Cabane; J. L. Cracowski; V. Riccieri; J. Distler; Z. Amoura; G. Valentini; P. Camaraschi; I. Tarner; C. Frances; P. Carpentier; N. C. Brembilla; O. Meyer; A. Kahan; C. Chizzolini; C. Boileau; Y. Allanore

doi:10.1002/art.30204

Association of the CD226 Ser³⁰⁷ variant with systemic sclerosis

P. Dieudé^*, M. Guedj, M. E. Truchetet, J. Wipff, L. Revillod, G. Riemekasten, M. Matucci-Cerinic, I. Melchers, E. Hachulla, P. Airo, E. Diot, N. Hunzelmann, L. Mouthon, J. Cabane, J. L. Cracowski, V. Riccieri, J. Distler, Z. Amoura, G. Valentini, P. CamaraschiI. Tarner, C. Frances, P. Carpentier, N. C. Brembilla, O. Meyer, A. Kahan, C. Chizzolini, C. Boileau, Y. Allanore

^*Korrespondierende/r Autor/-in für diese Arbeit

Klinik für Rheumatologie und klinische Immunologie

49 Zitate (Scopus)

Abstract

Objective: The nonsynonymous polymorphism rs763361 of the CD226 gene, which encodes DNAX accessory molecule 1, which is involved in T cell costimulation pathways, has recently been identified as a genetic risk factor for autoimmunity. The purpose of this study was to test for association of the CD226 rs763361 polymorphism with systemic sclerosis (SSc) in European Caucasian populations. Methods: CD226 rs763361 was genotyped in 3,632 individuals, consisting of a discovery sample (991 SSc patients and 1,008 controls) and a replication sample (999 SSc patients and 634 controls). All study subjects.

Originalsprache	Englisch
Zeitschrift	Arthritis and Rheumatism
Jahrgang	63
Ausgabenummer	4
Seiten (von - bis)	1097-1105
Seitenumfang	9
ISSN	0004-3591
DOIs	https://doi.org/10.1002/art.30204
Publikationsstatus	Veröffentlicht - 04.2011

Strategische Forschungsbereiche und Zentren

Forschungsschwerpunkt: Infektion und Entzündung - Zentrum für Infektions- und Entzündungsforschung Lübeck (ZIEL)

UN SDGs

Dieser Output leistet einen Beitrag zu folgendem(n) Ziel(en) für nachhaltige Entwicklung

Dokumente

10.1002/art.30204

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Dieudé, P., Guedj, M., Truchetet, M. E., Wipff, J., Revillod, L., Riemekasten, G., Matucci-Cerinic, M., Melchers, I., Hachulla, E., Airo, P., Diot, E., Hunzelmann, N., Mouthon, L., Cabane, J., Cracowski, J. L., Riccieri, V., Distler, J., Amoura, Z., Valentini, G., ... Allanore, Y. (2011). Association of the CD226 Ser³⁰⁷ variant with systemic sclerosis. Arthritis and Rheumatism, 63(4), 1097-1105. https://doi.org/10.1002/art.30204

@article{5478b9f1463743959bd7cfc0f173c49e,

title = "Association of the CD226 Ser307 variant with systemic sclerosis",

abstract = "Objective: The nonsynonymous polymorphism rs763361 of the CD226 gene, which encodes DNAX accessory molecule 1, which is involved in T cell costimulation pathways, has recently been identified as a genetic risk factor for autoimmunity. The purpose of this study was to test for association of the CD226 rs763361 polymorphism with systemic sclerosis (SSc) in European Caucasian populations. Methods: CD226 rs763361 was genotyped in 3,632 individuals, consisting of a discovery sample (991 SSc patients and 1,008 controls) and a replication sample (999 SSc patients and 634 controls). All study subjects.",

author = "P. Dieud{\'e} and M. Guedj and Truchetet, {M. E.} and J. Wipff and L. Revillod and G. Riemekasten and M. Matucci-Cerinic and I. Melchers and E. Hachulla and P. Airo and E. Diot and N. Hunzelmann and L. Mouthon and J. Cabane and Cracowski, {J. L.} and V. Riccieri and J. Distler and Z. Amoura and G. Valentini and P. Camaraschi and I. Tarner and C. Frances and P. Carpentier and Brembilla, {N. C.} and O. Meyer and A. Kahan and C. Chizzolini and C. Boileau and Y. Allanore",

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month = apr,

doi = "10.1002/art.30204",

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Dieudé, P, Guedj, M, Truchetet, ME, Wipff, J, Revillod, L, Riemekasten, G, Matucci-Cerinic, M, Melchers, I, Hachulla, E, Airo, P, Diot, E, Hunzelmann, N, Mouthon, L, Cabane, J, Cracowski, JL, Riccieri, V, Distler, J, Amoura, Z, Valentini, G, Camaraschi, P, Tarner, I, Frances, C, Carpentier, P, Brembilla, NC, Meyer, O, Kahan, A, Chizzolini, C, Boileau, C & Allanore, Y 2011, 'Association of the CD226 Ser³⁰⁷ variant with systemic sclerosis', Arthritis and Rheumatism, Jg. 63, Nr. 4, S. 1097-1105. https://doi.org/10.1002/art.30204

TY - JOUR

T1 - Association of the CD226 Ser307 variant with systemic sclerosis

AU - Dieudé, P.

AU - Guedj, M.

AU - Truchetet, M. E.

AU - Wipff, J.

AU - Revillod, L.

AU - Riemekasten, G.

AU - Matucci-Cerinic, M.

AU - Melchers, I.

AU - Hachulla, E.

AU - Airo, P.

AU - Diot, E.

AU - Hunzelmann, N.

AU - Mouthon, L.

AU - Cabane, J.

AU - Cracowski, J. L.

AU - Riccieri, V.

AU - Distler, J.

AU - Amoura, Z.

AU - Valentini, G.

AU - Camaraschi, P.

AU - Tarner, I.

AU - Frances, C.

AU - Carpentier, P.

AU - Brembilla, N. C.

AU - Meyer, O.

AU - Kahan, A.

AU - Chizzolini, C.

AU - Boileau, C.

AU - Allanore, Y.

PY - 2011/4

Y1 - 2011/4

N2 - Objective: The nonsynonymous polymorphism rs763361 of the CD226 gene, which encodes DNAX accessory molecule 1, which is involved in T cell costimulation pathways, has recently been identified as a genetic risk factor for autoimmunity. The purpose of this study was to test for association of the CD226 rs763361 polymorphism with systemic sclerosis (SSc) in European Caucasian populations. Methods: CD226 rs763361 was genotyped in 3,632 individuals, consisting of a discovery sample (991 SSc patients and 1,008 controls) and a replication sample (999 SSc patients and 634 controls). All study subjects.

AB - Objective: The nonsynonymous polymorphism rs763361 of the CD226 gene, which encodes DNAX accessory molecule 1, which is involved in T cell costimulation pathways, has recently been identified as a genetic risk factor for autoimmunity. The purpose of this study was to test for association of the CD226 rs763361 polymorphism with systemic sclerosis (SSc) in European Caucasian populations. Methods: CD226 rs763361 was genotyped in 3,632 individuals, consisting of a discovery sample (991 SSc patients and 1,008 controls) and a replication sample (999 SSc patients and 634 controls). All study subjects.

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