Antigen-presenting cells and tolerance induction

D. Von Bubnoff, H. De La Salle, J. Weßendorf, S. Koch, D. Hanau, T. Bieber*

*Korrespondierende/r Autor/-in für diese Arbeit
10 Zitate (Scopus)

Abstract

T cell tolerance induction to foreign and self-antigens has occupied research since the beginning of the understanding of the immune system. Much controversy still exists on this question even though new methods became available to investigate immunoregulatory mechanisms. Antigen-presenting cells play a pivotal role in transferring information from the periphery of the organism to lymphoid organs. There, they initiate not only the activation of naive T cells but seem to deliver important signals which result in T cell unresponsiveness with antigen-specific tolerance induction.

OriginalspracheEnglisch
ZeitschriftAllergy: European Journal of Allergy and Clinical Immunology
Jahrgang57
Ausgabenummer1
Seiten (von - bis)2-8
Seitenumfang7
ISSN0105-4538
DOIs
PublikationsstatusVeröffentlicht - 2002

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