A 87-year-old woman presented with a three-year history of partially erosive, partially bullous skin and mucosal lesions, symblepharon of both eyelids as well as dysphagia. To date, multiple excisions of the skin lesions, which had been described as "skin tumors" by surgeons, had been performed. The synopsis of histology, direct and indirect immunofluorescence established the diagnosis of anti-p200/anti-laminin gamma1 pemphigoid and BP180 NC16A/4575- positive mucous membrane pemphigoid with an unusual "epitope-spreading" phenomenon. Due to the late initiation of therapy, the disease-related loss of vision unfortunately was irreversible.
|Titel||Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete|
|ISBN (Print)||1432-1173 (Electronic)\r0017-8470 (Linking)|
|Publikationsstatus||Veröffentlicht - 2015|