Animal models for autoimmune bullous dermatoses

Katja Bieber; Shijie Sun; Norito Ishii; Michael Kasperkiewicz; Enno Schmidt; Misa Hirose; Jürgen Westermann; Xinhua Yu; Detlef Zillikens; Ralf J. Ludwig

doi:10.1111/j.1600-0625.2009.00948.x

Animal models for autoimmune bullous dermatoses

Katja Bieber, Shijie Sun, Norito Ishii, Michael Kasperkiewicz, Enno Schmidt, Misa Hirose, Jürgen Westermann, Xinhua Yu, Detlef Zillikens, Ralf J. Ludwig^*

^*Korrespondierende/r Autor/-in für diese Arbeit

Leibniz Forschungszentrum Borstel

37 Zitate (Scopus)

Abstract

Autoimmune bullous dermatoses are a group of severe diseases, which are clinically characterized by blisters and erosions of skin and/or mucous membranes. In order to investigate the pathogenesis of these potentially life-threatening diseases and to develop more specific therapeutic approaches, animal models have been developed that aim to reproduce the clinical, histological and immunopathological findings. We here review established and novel animal models of autoimmune skin blistering diseases and discuss their applications and limitations.

Originalsprache	Englisch
Zeitschrift	Experimental Dermatology
Jahrgang	19
Ausgabenummer	1
Seiten (von - bis)	2-11
Seitenumfang	10
ISSN	0906-6705
DOIs	https://doi.org/10.1111/j.1600-0625.2009.00948.x
Publikationsstatus	Veröffentlicht - 01.01.2010

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10.1111/j.1600-0625.2009.00948.x

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title = "Animal models for autoimmune bullous dermatoses",

abstract = "Autoimmune bullous dermatoses are a group of severe diseases, which are clinically characterized by blisters and erosions of skin and/or mucous membranes. In order to investigate the pathogenesis of these potentially life-threatening diseases and to develop more specific therapeutic approaches, animal models have been developed that aim to reproduce the clinical, histological and immunopathological findings. We here review established and novel animal models of autoimmune skin blistering diseases and discuss their applications and limitations.",

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AU - Bieber, Katja

AU - Sun, Shijie

AU - Ishii, Norito

AU - Kasperkiewicz, Michael

AU - Schmidt, Enno

AU - Hirose, Misa

AU - Westermann, Jürgen

AU - Yu, Xinhua

AU - Zillikens, Detlef

AU - Ludwig, Ralf J.

PY - 2010/1/1

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N2 - Autoimmune bullous dermatoses are a group of severe diseases, which are clinically characterized by blisters and erosions of skin and/or mucous membranes. In order to investigate the pathogenesis of these potentially life-threatening diseases and to develop more specific therapeutic approaches, animal models have been developed that aim to reproduce the clinical, histological and immunopathological findings. We here review established and novel animal models of autoimmune skin blistering diseases and discuss their applications and limitations.

AB - Autoimmune bullous dermatoses are a group of severe diseases, which are clinically characterized by blisters and erosions of skin and/or mucous membranes. In order to investigate the pathogenesis of these potentially life-threatening diseases and to develop more specific therapeutic approaches, animal models have been developed that aim to reproduce the clinical, histological and immunopathological findings. We here review established and novel animal models of autoimmune skin blistering diseases and discuss their applications and limitations.

UR - https://www.scopus.com/pages/publications/72549096651

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DO - 10.1111/j.1600-0625.2009.00948.x

M3 - Scientific review articles

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Animal models for autoimmune bullous dermatoses

Abstract

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