ANCA-ASSOZIIERTE VASKULITIDEN (WEGENER-GRANULOMATOSE, CHURG-STRAUSS-SYNDROM, MIKROSKOPISCHE POLYANGIITIS). 2. DIAGNOSTISCHES PROCEDERE

K. de Groot, A. Schnabel, W. L. Gross*

*Korrespondierende/r Autor/-in für diese Arbeit
9 Zitate (Scopus)

Abstract

The ANCA-associated vasculitides (Wegener's granulomatosis, Churg-Strauss syndrome, microscopic polyangiitis) are characterized by a broad spectrum of clinical manifestations and a highly variable clinical course. Due to greatly improved diagnostic techniques the number of newly diagnosed cases has increased rapidly within the past few years. This facilitated more individualized treatment and led to the concept of stage-adapted treatment. Immunodiagnostic parameters are being utilized inceasingly to supplement clinical and radiological findings. Inflammatory lesions are visualized by, for example, e.g. rhinoscopy, sinoscopy, and bronchoscopy or by radiological techniques including cranial and skeletal muscle magnetic resonance imaging, pulmonary high-resolution computed tomography, and digital subtraction angiography. These techniques not only serve to detect the extent of tissue and organ involvement, but also to direct bioptic procedures. Conventional histopathology must be supplemented by immunohistology in order to distinguish between the 'immune complex vasculitides' and the ANCA-associated 'pauci-immune vasculitides'.

Titel in ÜbersetzungANCA-associated vasculitides (Wegener's granulomatosis, Churg-Strauss syndrome, microscopic polyangiitis). 2. Diagnostical procedure
OriginalspracheDeutsch
ZeitschriftZeitschrift fur Rheumatologie
Jahrgang54
Ausgabenummer5
Seiten (von - bis)291-302
Seitenumfang12
ISSN0340-1855
PublikationsstatusVeröffentlicht - 1995

Strategische Forschungsbereiche und Zentren

  • Forschungsschwerpunkt: Infektion und Entzündung - Zentrum für Infektions- und Entzündungsforschung Lübeck (ZIEL)

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